Catamenial Hemoptysis

Cassina, Paolo C.; Hauser, Markus; Kacl, G. M.; Imthurn, Bruno; Schröder, S.; Weder, Walter

doi:10.1378/chest.111.5.1447

Cited by 76 publications

(31 citation statements)

References 10 publications

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“…For peripheral lesions, video-assisted thoracoscopic wedge resections have been successfully performed and this is considered as the preferred method of surgical treatment. In patients with centrally located bronchial endometriosis, subsegmentectomy, segmentectomy or lobectomy may be required [34, 38]. In a review of 229 cases of catamenial pneumothorax, adequate work-up was available for 195 patients (85.2%).…”

Section: Treatmentmentioning

confidence: 99%

Thoracic Endometriosis Syndrome

Augoulea

Lambrinoudaki²,

Christodoulakos³

2007

Respiration

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Endometriosis is defined as the presence of endometrial glands and stroma outside the uterine cavity and is usually confined to the pelvis. Thoracic endometriosis syndrome (TES) is a rare disorder characterized by the presence of functioning endometrial tissue in the pleura, the lung parenchyma and the airways. TES may present with hemoptysis, due to the shedding of endometrial tissue in the bronchial tree, or spontaneous pneumothorax or hemothorax if the endometrial tissue is localized peripherally. Patients are of reproductive age, often nulliparous, with long-standing symptoms. The crucial issue for establishing the diagnosis is the cyclicity of the symptoms which occur along with the menstrual cycle. TES is virtually a diagnosis of exclusion, established on clinical grounds, since neither CT nor endoscopy are specific for TES. Treatment consists of gonadotropin-releasing hormone analogues, aiming to suppress the hypophyseal-gonadal axis, so as to ensure a regression of the endometrial implants. If medical treatment fails, surgical resection of the endometriomas is suggested, although relapse rate may be high.

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Section: Treatmentmentioning

confidence: 99%

Thoracic Endometriosis Syndrome

Augoulea

Lambrinoudaki²,

Christodoulakos³

2007

Respiration

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“…11,12 Lymphatic and vascular transportation of the endometrium has also been proposed as a complimentary theory to explain rare cases of endometriosis occurring in unusual locations far from the pelvis, 13 but this is unlikely to be the primary mechanism of disease spread. [14][15][16] Another compelling proposal suggests that bone marrow-derived stem cells may differentiate into endometriotic tissue within and outside of endometrial cavity. 17 But the stem cell theory is primitive and not completely understood, although it is interesting.…”

Section: Introductionmentioning

confidence: 99%

Tubal origin of ovarian endometriosis

Zeng

Wang

et al. 2014

Modern Pathology

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Endometriosis is a puzzling and debilitating disease that affects millions of women around the world. Ovary is the most common organ site involved by endometriosis. Despite various hypotheses about its cell of origin, uncertainty remains. On the basis of our clinicopathologic observations, we hypothesize that fallopian tube may contribute the histogenesis of ovarian endometriosis. To examine if the hypothesis, tubal origin of ovarian endometriosis, has scientific supporting evidence, we identified a set of novel genes, which are either highly expressed in the normal fallopian tube or in the endometrium through a gene differential array study. Among many differentially expressed genes, FMO3 and DMBT1 were selected as the initial biomarkers to test the hypothesis. These biomarkers were then validated in ovarian sections with foci of endometriosis by comparing their expression levels in the fallopian tube and the endometrium within the same patients with real-time PCR, western blot and immunohistochemistry analysis. FMO3 was highly expressed in the tubal epithelia while low in the paired endometrium. In contrast, DMBT1 was high in the endometrium but low in the fallopian tube. In 32 ovarian endometriosis cases analyzed by real-time PCR, 18 (56%) showed a high level of FMO3 and a low level of DMBT1 expression. However, 14 (44%) endometriosis cases showed a reversed expression pattern with these two markers. Results were similarly seen in the methods of western blot and immunohistochemistry. The findings suggest that approximately 60% of the ovarian endometriosis we studied may be derived from the fallopian tube, whereas about 40% of the cases may be of endometrial origin. The fallopian tube epithelia may represent one of the tissue sources contributing to ovarian endometriosis. Such novel findings, which require confirmation, may have a significant clinical impact in searching for alternative ways of prevention and treatment of endometriosis.

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“…The etiological mechanisms remain to be elucidated, and optimal management is debated. Various treatment modalities such as surgery, hormonal therapy or conservative management have been attempted [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16]. However, the current knowledge on treatment outcomes of catamenial hemoptysis is largely based on case reports of patients with pelvic endometriosis.…”

Section: Introductionmentioning

confidence: 99%

Catamenial Hemoptysis: A Nationwide Analysis in Korea

et al. 2009

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Background: Hemoptysis is a potentially serious clinical problem. However, there is no consensus on the clinical characteristics, treatment and patient outcome of catamenial hemoptysis. Objective: Clinical characteristics, treatments and outcome in patients of catamenial hemoptysis were evaluated. Methods: We conducted a retrospective nationwide observational analysis of Korean patients with catamenial hemoptysis. Results: Nineteen patients with catamenial hemoptysis were evaluated from 13 tertiary-care hospitals in Korea. The median age of the patients was 25 years; 8 (42%) were ever-smokers. Eight patients were pathologically diagnosed; 11 were diagnosed by clinical criteria. Sixteen (84%) patients had a history of obstetric or gynecological procedures before developing hemoptysis. The mean amount of hemoptysis (mean ± SD) was 58.3 ± 71.3 for surgery, 46.4 ± 33.2 for hormonal and 29.1 ± 26.3 for conservative treatment groups. Hemoptysis did not recur in 8 (89%) of 9 patients after surgery. None of the patients in the hormonal or conservative treatment groups had persistent hemoptysis. There was an excellent outcome (complete remission and partial responses) in all patients with conservative treatment, suggesting that endometrial cells implanted into the lung may have a benign course. Conclusion: Patients without massive hemoptysis can be treated conservatively or with hormonal agents.

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Catamenial Hemoptysis

Cited by 76 publications

References 10 publications

Thoracic Endometriosis Syndrome

Thoracic Endometriosis Syndrome

Tubal origin of ovarian endometriosis

Catamenial Hemoptysis: A Nationwide Analysis in Korea

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