Catalytic approach green synthesis, characterization and electrochemical studies of heterocyclic azo dye derived from 5-amino-1,3,4-thiadiazole-2-thiol

Harisha, S.; Keshavayya, J.; Swamy, B.E. Kumara; Sivaprakasam, Prasanna; Viswanath, C.C.; Ravi, B. N.

doi:10.1016/j.molliq.2018.10.156

Cited by 11 publications

(3 citation statements)

References 34 publications

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“…By keeping these concerns in mind, a new and convenient method was reported for the synthesis of 5-[( E) ]-(5-sulfanyl-1,3,4-thiadiazol-2-yl)diazenyl]-6-thioxo-dihydropyrimidine-2,4(1 H ,3 H )dione by the diazo coupling of 5-amino-1,3,4 thiadiazole-2-thiol with thio-barbituric acid under solvent free conditions without using any catalyst. The comparison was made in terms of duration of reaction and product yield with the conventional approaches, it was concluded that the solvent-free approach was advantageous in terms of cost-effectiveness, simplicity of experimental design and recovery of product [ 57 ]. A series of diazenyl Schiff bases was synthesized by reacting salicylaldehyde incorporating azo derivatives with substituted aromatic amines in the presence of acetic acid as a catalyst.…”

Section: Therapeutic Potential Of Azo Moietymentioning

confidence: 99%

Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives

et al. 2021

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Synthetic heterocyclic compounds have incredible potential against different diseases; pyridines, phenolic compounds and the derivatives of azo moiety have shown excellent antimicrobial, antiviral, antidiabetic, anti-melanogenic, anti-ulcer, anticancer, anti-mycobacterial, anti-inflammatory, DNA binding and chemosensing activities. In the present review, the above-mentioned activities of the nitrogen-containing heterocyclic compounds (pyridines), hydroxyl (phenols) and azo derivatives are discussed with reference to the minimum inhibitory concentration and structure–activity relationship, which clearly indicate that the presence of nitrogen in the phenyl ring; in addition, the hydroxyl substituent and the incorporation of a diazo group is crucial for the improved efficacies of the compounds in probing different diseases. The comparison was made with the reported drugs and new synthetic derivatives that showed recent therapeutic perspectives made in the last five years.

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Section: Therapeutic Potential Of Azo Moietymentioning

confidence: 99%

Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives

et al. 2021

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“…The above class of compounds played a role in the governance of the dye and printing market [19] . In contrast, the nitrogen atom (−N + ≡N) moiety has been extensively explored as a nucleophile acceptor and this moiety produces a wide range of colors by changing various heterocyclic or non‐heterocyclic coupling components [20–24] …”

Section: Introductionmentioning

confidence: 99%

“…[19] In contrast, the nitrogen atom (À N + �N) moiety has been extensively explored as a nucleophile acceptor and this moiety produces a wide range of colors by changing various heterocyclic or non-heterocyclic coupling components. [20][21][22][23][24] It is well documented in the literature that the introduction of azo-functionality in the chemosensors increases their chromogenic ability, which contains heterocyclic azo colorants found to increase chromophoric strength. The environment and human health are harmed by some ions produced by industries and chemical warfare weapons like sarin, soman, and tabun that come from degradation products (hydrolysis).…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, and Photophysical Probing Interaction Studies on Azo‐Sulfonamides Acting as Potent Anti‐Tubercular Agents

Krishnamurthy,

Keshavayya,

Yesudhasan

et al. 2023

ChemistrySelect

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By utilizing the sulfamethizole component via the diazo‐coupling approach by electrophilic substitution process, an unprecedented series of four mono‐azo sulfonamide molecules were synthesized in good yield. Spectroscopic investigation unambiguously confirmed the structures of the newly synthesized mono‐azo sulfonamide derivatives, including FT‐IR, NMR (1H and 13C), HRMS, Uv‐Vis, and Photoluminescence (PL). In a variety of organic solvents, the 3‐diethylaminophenol coupled azo‐sulfonamide T3 showed a maximum bathochromic shift of λmax in the range 462–479 nm and in the region of 88–142 nm, a derivative of 2‐hydroxy‐1,4‐naphthoquinone T4 coupled azo colourant showed a significant Stokes shift. Conceptual density function theory was also used to build a new family of high energy density energetic mono‐azo sulfonamides. Frontier molecular orbitals (HOMO‐LUMO) and global reactivity descriptors were identified to analyze how molecules interact with one another. Further, the potency of the anti‐tubercular activity of the colorants was examined with the standards such as Isoniazid, Ethambutol, Pyrazinamide, Rifampicin, and Streptomycin. The results indicated that‐ Lawsone pigment (2‐hydroxy‐1,4‐naphthoquinone) incorporated azo molecule T4 displayed the sensitivity at 3.12 μg/mL compared with other the three mono‐azo molecules.

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Novel hydrazono-hydrazonoyl chlorides containing pyrazole moiety for concurrent dyeing and practical finishing of cotton fabrics

Abdel‐Wahab

Mohamed

Fahmy

2020

Journal of Materials Research and Technology

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Catalytic approach green synthesis, characterization and electrochemical studies of heterocyclic azo dye derived from 5-amino-1,3,4-thiadiazole-2-thiol

Cited by 11 publications

References 34 publications

Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives

Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives

Synthesis, Characterization, and Photophysical Probing Interaction Studies on Azo‐Sulfonamides Acting as Potent Anti‐Tubercular Agents

Novel hydrazono-hydrazonoyl chlorides containing pyrazole moiety for concurrent dyeing and practical finishing of cotton fabrics

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