Catalytic Amination of Biomass‐Based Alcohols

Abstract

Can I borrow hydrogen? Direct amination of biomass‐derived platform alcohols can be efficiently performed through the borrowing hydrogen mechanism, offering high activity and selectivity at low‐to‐moderate temperatures. Unlike nucleophilic substitution, the catalyst behaves as a tandem system involving the temporary removal of H2 from the reaction medium.

Combining bio- and chemo-catalysis for the conversion of bio-renewable alcohols: homogeneous iridium catalysed hydrogen transfer initiated dehydration of 1,3-propanediol to aldehydes

“…3,10,23 Of specific interest is the potential of hydrogen transfer and dehydrogenation catalysts to transform bio-renewable alcohols into value added chemicals. 24,25 Reactions that involve the transfer of hydrogen from one organic donor to another (sometimes termed "hydrogen borrowing" reactions) have huge potential in organic synthesis, and have been the subject of several recent reviews. [24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] Typically these reactions employ a transition metal catalyst (most commonly an organometallic Ru or Ir complex) and a base to activate an alcohol by deprotonation and extraction of hydride from the -position.…”

Plasma‐Made (Ni0.5Cu0.5)Fe2O4 Nanoparticles for Alcohol Amination under Microwave Heating

“…Amines are essential synthetic building blocks for the chemical industry and for numerous biological processes . Synthetic amines are widely employed in pesticides, pharmaceuticals, dyes, detergents, polymers, lubricants and various other functional materials . For their synthesis, a wide variety of processes is available, such as using halides or tosylates as alkylating agents through the Buchwald‐Hartwig coupling.…”

“…[1] Synthetic amines are widely employed in pesticides, pharmaceuticals, dyes, detergents, polymers, lubricants and various other functional materials. [2] For their synthesis, a wide variety of processes is available, such as using halides or tosylates as alkylating agents through the Buchwald-Hartwig coupling. However, these coupling partners are toxic, and generate stoichiometric amounts of salts as byproducts.…”

Reductive Amination of 2-Amino-2-methyl-1-propanol and Ammonia to Produce 2-Methyl-1,2-propanediamine over Raney Nickel Catalyst

“…Among the methods for commercial production of amines, by far the largest and most utilized are based on the reaction of alcohols with ammonia . The catalytic amination of alcohols is an atom‐economical and environmentally attractive method for the synthesis of organic amines, thanks to the ubiquitous availability of alcohols . Thus, selective, catalytic synthesis of diamines from diols and ammonia is highly desirable.…”