Catalase-like quantum dots of l-lysine polymerization as free radical scavengers for hypoxic brain injury

Li, Qifeng; Gao, Yalong; Shen, Jun; Mu, Xiaoyu; Wang, Junying; Ouyang, Lufei; Chen, Ke; He, Hua; Pei, Jiahui; Ren, Qinjuan; Sun, Si; Liu, Haile; Zhou, Lei; Sun, Yang; Long, Wei; Zhang, Jianning; Zhang, Xiaodong

doi:10.1016/j.mtcomm.2021.102286

Cited by 9 publications

(5 citation statements)

References 51 publications

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“…To mimic the enzymatic activity of CAT, many metalcontaining and carbon-based nanomaterials have been developed [83][84][85][86][87][88][89][90][91]. For instance, Dan and coworkers designed indocyanine green-loaded ultrasmall gold nanoclusters (Au NCs-ICG) that had a similar catalytic capability to CAT but not POD or SOD (Fig.…”

Section: Cat-like Nanozymesmentioning

confidence: 99%

Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy

2022

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Natural enzymes usually suffer from high production cost, ease of denaturation and inactivation, and low yield, making them difficult to be broadly applicable. As an emerging type of artificial enzyme, nanozymes that combine the characteristics of nanomaterials and enzymes are promising alternatives. On the one hand, nanozymes have high enzyme-like catalytic activities to regulate biochemical reactions. On the other hand, nanozymes also inherit the properties of nanomaterials, which can ameliorate the shortcomings of natural enzymes and serve as versatile platforms for diverse applications. In this review, various nanozymes that mimic the catalytic activity of different enzymes are introduced. The achievements of nanozymes in different cancer diagnosis and treatment technologies are summarized by highlighting the advantages of nanozymes in these applications. Finally, future research directions in this rapidly developing field are outlooked."Image missing"

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Section: Cat-like Nanozymesmentioning

confidence: 99%

Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy

2022

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“…The major problem regarding the generation of reactive oxygen species or free radicals in biological systems could be scavenged or neutralized by nanomaterials having good antioxidant activity [21,[35][36][37][38]. The CDs have both electron donors and acceptors capability that makes them act as good antioxidant and prooxidant agents [39][40][41] The CDs are a less explored and more suitable candidate for antioxidant study due to their minimal toxicity [3,4,31].…”

Section: Dpph Free Radical Scavenging Activitymentioning

confidence: 99%

Hydrothermal synthesis of PVP-passivated clove bud-derived carbon dots for antioxidant, catalysis, and cellular imaging applications

Pandey

Bankoti²,

Nath³

et al. 2022

Colloids and Surfaces B: Biointerfaces

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“…Catalase's important role may limit the effects of oxidant molecules in tissues and act in cellular defence against oxidative cell damage due to its free radical scavenging characteristics. (33) The current findings showed that oral administration of chromium VI led in organ failure, as evidenced by a 25% decrease in catalase levels in the liver and kidney. As a result, the current findings lead to the conclusion that Hexavalent chromium had detrimental effects via increasing free radicals.…”

Section: Discussionmentioning

confidence: 49%