Cat-scratch disease simulating a malignant process of the chest wall

Abstract

The present case emphasizes the wide spectrum of clinical manifestations associated with cat-scratch disease which should be investigated as differential diagnosis of manifestations suggesting a neoplastic disease in children.

Detection of Bartonella henselae and Bartonella clarridgeiae DNA in hepatic specimens from two dogs with hepatic disease

“…The genus Bartonella is composed of a group of fastidious, gram-negative bacteria well-adapted to persist intracellularly in humans and animals. [6][7][8] Bartonella infection is a well-documented cause of local or diffuse tissue injury in people, [1][2][3][9][10][11][12][13][14][15][16] and infections caused by Bartonella spp in human beings have been associated with a wide variety of granulomatous syndromes ranging from classic lymphadenopathy and fever (cat scratch disease) to osteomyelitis, hepatosplenitis, and ocular and thoracic disease. 1,[6][7][8][9][10] In general, the prevalence of granulomatous disease in humans has risen with the increased incidence of AIDS and the more frequent use of immunosuppressive therapy.…”

“…[6][7][8] Bartonella infection is a well-documented cause of local or diffuse tissue injury in people, [1][2][3][9][10][11][12][13][14][15][16] and infections caused by Bartonella spp in human beings have been associated with a wide variety of granulomatous syndromes ranging from classic lymphadenopathy and fever (cat scratch disease) to osteomyelitis, hepatosplenitis, and ocular and thoracic disease. 1,[6][7][8][9][10] In general, the prevalence of granulomatous disease in humans has risen with the increased incidence of AIDS and the more frequent use of immunosuppressive therapy. 11 There has also been an increase in the number of reports of Bartonella-induced granulomatous hepatitis because of enhanced clinical recognition of this important disease and improved diagnostic capabilities following the isolation and identification of B henselae in 1992.…”