Cat-scratch disease presenting as parotid gland abscess and aseptic meningitis

García, Juan Carlos García; Fernández, M. J. Núñez; Portillo, Aránzazu; Oteo, José A.

doi:10.1016/j.eimc.2016.06.003

Cited by 5 publications

(1 citation statement)

References 8 publications

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“…Documentation of human Bartonella infections is scarce in Spain. Nevertheless, clinical descriptions [ 5 , 17 , 26 ] and seroepidemiological studies about the prevalence of B. henselae/B. quintana [ 27 – 29 ] have been reported.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain

et al. 2017

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BackgroundThe genus Bartonella includes fastidious, facultative intracellular bacteria mainly transmitted by arthropods and distributed among mammalian reservoirs. Bartonella spp. implicated as etiological agents of zoonoses are increasing. Apart from the classical Bartonella henselae, B. bacilliformis or B. quintana, other species (B. elizabethae, B. rochalimae, B. vinsonii arupensis and B. v. berkhoffii, B. tamiae or B. koehlerae, among others) have also been associated with human and/or animal diseases. Laboratory techniques for diagnosis (culture, PCR assays and serology) usually show lack of sensitivity. Since 2005, a method based on a liquid enrichment Bartonella alphaproteobacteria growth medium (BAPGM) followed by PCRs for the amplification of Bartonella spp. has been developed. We aimed to assess culture, molecular and serological prevalence of Bartonella infections in companion animal veterinary personnel from Spain.MethodsEach of 89 participants completed a questionnaire. Immunofluorescence assays (IFA) using B. vinsonii berkhoffii (genotypes I, II and III), B. henselae, B. quintana and B. koehlerae as antigens were performed. A cut-off of 1:64 was selected as a seroreactivity titer. Blood samples were inoculated into BAPGM and subcultured onto blood agar plates. Bartonella spp. was detected using conventional and quantitative real-time PCR assays and DNA sequencing.ResultsAmong antigens corresponding to six Bartonella spp. or genotypes, the lowest seroreactivity was found against B. quintana (11.2%) and the highest, against B. v. berkhoffii genotype III (56%). A total of 27% of 89 individuals were not seroreactive to any test antigen. Bartonella spp. IFA seroreactivity was not associated with any clinical sign or symptom. DNA from Bartonella spp., including B. henselae (n = 2), B. v. berkhoffii genotypes I (n = 1) and III (n = 2), and B. quintana (n = 2) was detected in 7/89 veterinary personnel. PCR and DNA sequencing findings were not associated with clinical signs or symptoms. No co-infections were observed. One of the two B. henselae PCR-positive individuals was IFA seronegative to all tested antigens whereas the other one was not B. henselae seroreactive. The remaining PCR-positive individuals were seroreactive to multiple Bartonella spp. antigens.ConclusionsHigh serological and molecular prevalences of exposure to, or infection with, Bartonella spp. were found in companion animal veterinary personnel from Spain. More studies using BAPGM enrichment blood culture and PCR are needed to clarify the finding of Bartonella PCR-positive individuals lacking clinical symptoms.Electronic supplementary materialThe online version of this article (10.1186/s13071-017-2483-z) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain

et al. 2017

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Neurological presentations of Bartonella henselae infection

et al. 2018

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Clinical characteristics that predict parotid abscess: An observational cohort study

Srivanitchapoom

Yata

2021

Annals of Medicine &Amp; Surgery

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Background We analysed clinical factors that are predictive of a diagnosis of parotid abscess among patients with bacterial parotitis. Material and methods This retrospective study included 64 hospitalised patients who were diagnosed with parotid abscess, or bacterial parotitis. Data on patient demographics, clinical characteristics, and clinical management were collected. Predictive factors for parotid abscess were evaluated using univariate and multivariate analysis. Results There were 25 patients with parotid abscess and 39 with bacterial parotitis. All patients presented with moderate-to-severe disease, required parenteral antibiotics, or had indicators for surgical drainage. Patient profiles and immune status were not significantly associated with parotid abscess. However, parameters that were significantly related to parotid abscess were subacute presentation (approximate 10.4 days) (p value = 0.016), fluctuation (p value < 0.001), and normal (haemoglobin) Hb level >12–13 g/dL (p value = 0.035). Imaging indicated the abscess location, extension and evaluated the complications. Surgical drainage with small skin incision and antibiotic coverage for possible pathogens, in particular Staphylococcus spp. and Streptococcus spp. produced favourable patient outcomes. Complication was identified in 3 cases with included septicaemia and cellulitis of the face and parapharyngeal space. Conclusions Among bacterial parotitis patients, parotid abscess should be considered in whom presented with subacute duration of symptoms, enlarged glands with fluctuation, and non-anaemic problem. Instead of standard skin incision of parotidectomy, small vertical skin incision over a well localised abscess pocket or fluctuated area achieved the good results.

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Cat-scratch disease presenting as parotid gland abscess and aseptic meningitis

Cited by 5 publications

References 8 publications

Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain

Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain

Neurological presentations of Bartonella henselae infection

Clinical characteristics that predict parotid abscess: An observational cohort study

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