Cat scratch disease in Japan

Clinical implication of prolonged fever in children with cat scratch disease

“…On the other hand, 52 (40.9%) belonged to "atypical CSD," presenting with prolonged fever of more than 7 days, with systemic complications, or without lymphadenopathy. With regard to the prevalence of atypical cases, our figure of prevalence is conspicuously higher than that in the literature, 3,20,21 although it is difficult to obtain comparable statistics from the literature. The previous reports 2,3,22 investigated child and adult cases together, while this report focused on child cases only.…”

“…Of the 127 cases, 120 (94.5%) were associated with injury or contact with a cat, whereas the other 7 (5.5%) denied it, suggesting possible transmission from other pets, such as dogs, hamsters, or ferrets. 15,20,21 Our study revealed a broad spectrum of clinical manifestations in CSD. Of the 127 seropositive cases, 75 (59.1%) had a typical CSD, presenting with regional lymphadenopathy, a short period of self-limiting fever, and general symptoms.…”

MR Signal Changes in a Child with Cat Scratch Disease Encephalopathy and Status Epilepticus

“…In our case, it seems likely that the prolonged seizures from the right temporoparietal cortical regions induced abnormal neural discharges in the thalamic nuclei leading to the MR signal changes seen in the ipsilateral pulvinar. Cervicocephalic arterial dissection (CAD) should always be considered as the cause of stroke in young and middle-aged patients, particularly when traditional risk factors are absent [1][2][3]. CAD can occur spontaneously or in relation with trauma and vasculopathy.…”

“…On the 19th day, she was fully conscious and appeared neurologically normal. Four days later, she was discharged from hospital.We investigated the possible infection of the pet cat and dog as well as her family members with B. henselae by measuring indirect fluorescence IgG titers for B. henselae [1]. Among the 7 family members, the patient, her grandfather and grandmother were seropositive with titers being 1:512, 1:64 and 1:128, respectively, while the parents and brother and sister were seronegative.…”

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Cat scratch disease (CSD) typically is a self-limited regional lymphadenopathy of children and young adults caused by Bartonella henselae [1]. Although CSD is generally mild in symptomatology, many systemic complications have been described.

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