Castleman Disease: A Case with Atypical Presentation

Abstract

Castleman disease is a benign lymphoproliferative disorder characterized by enlarged lymph nodes. In children the disease is rare, usually localized, and asymptomatic. Resection of the node is almost always curative. A case is reported that was diagnosed as hyaline vascular-type Castleman disease at 1 year of age. The disease recurred from infraclavicular region in addition to primary site, even though total excision was performed. Although the disease is mullticentric after recurrence, the patient has no systemic symptoms.

Castleman's disease in childhood: report of three cases and review of the literature

“…Since the recurrence of localized CD is very unusual when the resection is complete, surgery is the preferred treatment in these cases [6-8,29-31]. When a complete resection is impossible, in the case of unicentric hyaline-vascular disease, partial resection and/or, radiation therapy with doses ranging from 27 to 45 Gy are a possibility [7,32,33].…”

Castleman’s Disease of the Pleura: Case Presentation and Review of Literature

“…Cases of unicentric castleman's disease have a high cure rate with complete surgical excision. The chances of recurrence after surgical excision are rare; there are reported cases where the disease recurred after 1, 9, 18 and 20 years [5,[20][21][22][23].…”