Castes, Migration, Immunogenetics and Infectious Diseases in South India

Pitchappan, Ramasamy

doi:10.1159/000066329

Cited by 34 publications

(15 citation statements)

References 10 publications

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“…Spatial variation and localization in parasite adaptation against hosts and in host adaptation against parasites, or said differently, in host immune maladaptation against out-group-typical parasites, is a general pattern in the animal and plant infectious disease literature [19,20]. Human cases showing this include (i) the caste-specific infectious diseases and corresponding specific immunity among sympatric castes in India [21], and (ii) the village-specific immune defences against leishmania parasites in adjacent Sudanese villages [22] (also see [9]). …”

Section: Parasite-stress Theory Of Valuesmentioning

confidence: 99%

Parasite stress promotes homicide and child maltreatment

Thornhill

Fincher

2011

Phil. Trans. R. Soc. B

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Researchers using the parasite-stress theory of human values have discovered many cross-cultural behavioural patterns that inform a range of scholarly disciplines. Here, we apply the theory to major categories of interpersonal violence, and the empirical findings are supportive. We hypothesize that the collectivism evoked by high parasite stress is a cause of adult-on-adult interpersonal violence. Across the US states, parasite stress and collectivism each positively predicts rates of men's and women's slaying of a romantic partner, as well as the rate of male-honour homicide and of the motivationally similar felony-related homicide. Of these four types of homicide, wealth inequality has an independent effect only on rates of male-honour and felony-related homicide. Parasite stress and collectivism also positively predict cross-national homicide rates. Child maltreatment by caretakers is caused, in part, by divestment in offspring of low phenotypic quality, and high parasite stress produces more such offspring than low parasite stress. Rates of each of two categories of the child maltreatment-lethal and non-lethal-across the US states are predicted positively by parasite stress, with wealth inequality and collectivism having limited effects. Parasite stress may be the strongest predictor of interpersonal violence to date.

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Section: Parasite-stress Theory Of Valuesmentioning

confidence: 99%

Parasite stress promotes homicide and child maltreatment

Thornhill

Fincher

2011

Phil. Trans. R. Soc. B

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“…The MHC class I and class II gene HLA-DRB1*02, DRB1*1501 North Eastern Indian [77] No particular HLA type confirmed South India [78,79] HLA-DR2 Iranian [80] HLA-DRB1*07, DQA1*0101 HLA-DQA1*0301, *0501 Thais [81] HLA-DQB1*0502 DQA1*0601, DQB1*0301…”

Section: Hivmentioning

confidence: 99%

HLA and disease

Ghodke‐Puranik

Joshi

Chopra³

et al. 2005

Eur J Epidemiol

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Association of HLA and diseases is well known. Several population studies are available suggesting evidence of association of HLAs in more than 40 diseases. HLA found across various populations vary widely. Some of the reasons attributed for such variation are occurrence of social stratification based on geography, language and religion, consequences of founder effect, racial admixture or selection pressure due to environmental factors. Hence certain HLA alleles that are predominantly associated with disease susceptibility or resistance in one population may or may not show any association in other populations for the same disease. Despite of these limitations, HLA associations are widely studied across the populations worldwide and are found to be important in prediction of disease susceptibility, resistance and of evolutionary maintenance of genetic diversity. This review consolidates the HLA data on some prominent autoimmune and infectious diseases among various ethnic groups and attempts to pinpoint differences in Indian and other population.

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“…Dating back to time immemorial, this system is characterized by its well stratified, endogamous and close-cultural values, which could strongly prohibit any exchange from outside. Genetically, this restriction significantly control the gene flow between the population subgroups, which creates specific genetic patterns, that could make the groups either susceptible or resistant to various diseases [2][3].…”

Section: Introductionmentioning

confidence: 99%

Association of ACE <i>DD</i> Genotype with Hypertension among the Tribal Populations of South India

Paramasivam

Nandakumar

Arumugam

et al. 2016

ILNS

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The Renin-Angiotensin System (RAS) is an important regulator of the blood pressure(BP). The level of the vasoactive peptide Angiotensin-II, is mainly determined by the RAS enzyme, angiotensin converting enzyme-1 (ACE-1). Polymorphisms in ACE gene is reported to be associated with hypertension in various populations worldwide. We investigated the association of ACE I/D polymorphisms with hypertension among the tribal populations of South India. Samples were collected from hypertensive patients (n = 33) and healthy controls (n = 37). Genotyping was performed using Polymerase chain reaction (PCR) with allele specific primers. The DD genotype is significantly observed among the cases (OR = 1.0) . Specifically, the DD genotype is more evident among the females (OR = 0.705) than males (OR = 1.22) and is analysed to be associated with hypertension among the tribal populations of South India.

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Castes, Migration, Immunogenetics and Infectious Diseases in South India

Cited by 34 publications

References 10 publications

Parasite stress promotes homicide and child maltreatment

Parasite stress promotes homicide and child maltreatment

HLA and disease

Association of ACE <i>DD</i> Genotype with Hypertension among the Tribal Populations of South India

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