Caseating granulomas manifesting as aseptic abscesses in the setting of ulcerative colitis

Herskovitz, Ingrid; Alonso‐Llamazares, Javier

doi:10.1111/ijd.13886

Cited by 4 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Histopathological examinations have shown predominant infiltration of neutrophils around the granulomatous tissue and sterile abscesses. The systemic administration of steroids is the most common induction treatment, and the efficacy of anti-tumor necrosis factor-α (TNF-α) antibody in addition to steroid pulse therapy and immunosuppressants has been recently reported in some refractory cases (Table 2) (1,(6)(7)(8). An AA diagnosis is a diagnosis of exclusion, and there is currently no established diagnostic method.…”

Section: Discussionmentioning

confidence: 99%

Rapidly Progressing Aseptic Abscesses in a Patient with Ulcerative Colitis

Yamaguchi

Nakagawa

et al. 2021

Intern. Med.

View full text Add to dashboard Cite

Aseptic abscesses (AAs) are extraintestinal manifestations of inflammatory bowel disease (IBD). IBDassociated AAs are rare in Japan. We treated a 45-year-old man with ulcerative colitis (UC)-associated AAs. During remission, multiple progressive abscesses were detected in the spleen; he underwent splenectomy because an infectious disease was suspected. Although his condition improved temporarily after splenectomy, a large liver abscess was noted, and a diagnosis of UC-associated AAs was made. Granulocytapheresis (GCAP) and infliximab (IFX) administration resolved the abscess. This is the first reported case of UC-associated AAs in a Japanese patient treated by splenectomy, GCAP, and IFX.

show abstract

Section: Discussionmentioning

confidence: 99%

Rapidly Progressing Aseptic Abscesses in a Patient with Ulcerative Colitis

Yamaguchi

Nakagawa

et al. 2021

Intern. Med.

View full text Add to dashboard Cite

show abstract

Multiple ulcerative colitis-associated aseptic abscesses successfully treated with infliximab: a case report

Toba

Ikegami

Nogami

et al. 2023

Clin J Gastroenterol

View full text Add to dashboard Cite

Recurrent multiple cutaneous aseptic abscesses with spontaneous regression: An unusual case report

Kessoku

Nakamura

Ishitsuka

et al. 2020

The Journal of Dermatology

View full text Add to dashboard Cite

Additionally, our case shows HLA-Cw1, which is associated with Sweet's disease (SD), especially with neurological involvement. 5 Therefore, given the isolated cutaneous involvement, the pathogenesis of our case may be close to SD, which would also show cutaneous neutrophilic infiltration, although the diagnosis of AA was made based on histological findings of abscesses surrounded by granulomatous reaction in all examined nodules. Steroid therapy is typically required for remission of AA. 1 In contrast, all of the lesions in our case spontaneously regressed, which has not been previously reported. Additionally, our case showed isolated cutaneous involvement, suggesting a non-aggressive form. However, AA sometimes precedes development of systemic diseases and cases involving other organs or development of systemic diseases appearing several years after AA diagnosis have been reported. 1 Moreover, given that our case has HLA-Cw1, significantly associated with neuro-SD, long-term follow up, including neurological as well as intestinal examinations, is necessary.

show abstract

Caseating granulomas manifesting as aseptic abscesses in the setting of ulcerative colitis

Abstract: Case report Aseptic abscesses in the setting of ulcerative colitis Herskovitz, Maderal, and Alonso-Llamazares

Cited by 4 publications

References 8 publications

Rapidly Progressing Aseptic Abscesses in a Patient with Ulcerative Colitis

Rapidly Progressing Aseptic Abscesses in a Patient with Ulcerative Colitis

Multiple ulcerative colitis-associated aseptic abscesses successfully treated with infliximab: a case report

Recurrent multiple cutaneous aseptic abscesses with spontaneous regression: An unusual case report

Contact Info

Product

Resources

About