Aseptic abscesses (AAs) are extraintestinal manifestations of inflammatory bowel disease (IBD). IBDassociated AAs are rare in Japan. We treated a 45-year-old man with ulcerative colitis (UC)-associated AAs. During remission, multiple progressive abscesses were detected in the spleen; he underwent splenectomy because an infectious disease was suspected. Although his condition improved temporarily after splenectomy, a large liver abscess was noted, and a diagnosis of UC-associated AAs was made. Granulocytapheresis (GCAP) and infliximab (IFX) administration resolved the abscess. This is the first reported case of UC-associated AAs in a Japanese patient treated by splenectomy, GCAP, and IFX.
system employing a combination ofP.d lysates and T7 RNA polymerase. W{th this system, three subun{ts ofP.dCeO were synthesized, a]though the amount is ]ow. Optimization of the system is now in progress.
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