Case study: A unique approach to compliance in a patient with venous ulcers

Christensen, C; Yeager, Anson

doi:10.1067/mvn.2001.115783

Cited by 6 publications

(7 citation statements)

References 4 publications

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“…Using two‐dimensional gel electrophoresis a ‘wound map’ from untreated eschar was obtained. Of the proteins identified many were potentially derived from fibrin cuffs, which in the wound environment seal off blood vessels interfering with oxygen and nutrient delivery and trapping growth factors necessary for wound healing 16,17 . Maggot recombinant chymotrypsin I incubated with wound eschar degraded all of the fibrin‐derived proteins in the eschar with only α1 antitrypsin, MRP 14/calprotectin and some residual IgG 1 heavy chain being resistant to digestion.…”

Section: Discussionmentioning

confidence: 99%

Degradation of eschar from venous leg ulcers using a recombinant chymotrypsin from Lucilia sericata

Telford

Brown

Seabra

et al. 2010

British Journal of Dermatology

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Section: Discussionmentioning

confidence: 99%

Degradation of eschar from venous leg ulcers using a recombinant chymotrypsin from Lucilia sericata

Telford

Brown

Seabra

et al. 2010

British Journal of Dermatology

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“… 59 Further analysis of the 69 articles identified 23 studies attempting to directly influence adherence through modifying one or more variables, including 14 RCTs 42 , 43 , 45 , 50–53 , 57 , 58 , 60–64 and nine case studies (or case series). 30 , 32 , 46–49 , 65–67 These were categorized by study design, and by the number and type of variables that were modified. The variables investigated are represented in Figure 5 .…”

Section: Resultsmentioning

confidence: 99%

“…Nine case studies/series described successful attempts to influence adherence. Six of these studies [46][47][48][49]66,67 used personalized novel approaches to garment prescription (Velcro wraps, grip tops, zippers and compression kits) while three 30,32,65 advocated for a personalized collaborative approach, involving health professionals and significant others in patient care. Eight of the nine case studies/series 30,32,[46][47][48][49]65,66 reported on a personalized multidimensional intervention, modifying at least two variables in the treatment plan.…”

Section: Developing a Conceptual Frameworkmentioning

confidence: 99%

Improving Adherence to Wearing Compression Stockings for Chronic Venous Insufficiency and Venous Leg Ulcers: A Scoping Review

Bar¹,

Brandis²,

Marks³

2021

PPA

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Purpose Patient adherence to wearing compression stockings in the management of chronic venous insufficiency (CVI) and venous leg ulcers (VLUs) is low. Poor adherence with compression stockings contributes to recurrence and impaired healing of VLUs. As such, the purpose of this review was to report on the scientific evidence related to adherence and explore modifiable factors which impact adherence with compression stockings. Methods A systematic search was conducted from inception to 31 October 2019. Following the PRISMA-ScR Checklist, PubMed, Medline, CINAHL, Cochrane, Embase, OT Seeker and Web of Science were explored using search terms: compression/compression stocking/compression garment/compression sock/stockings/garments and adherence/compliance/concordance. Results We identified 2613 papers of which 125 full text papers were assessed for eligibility and 69 met inclusion criteria. Papers were grouped and charted by concepts relevant to the research questions and narratively synthesized. Several dominant themes emerged, and a conceptual framework was developed incorporating modifiable variables, adherence itself, and outcomes related to adherence. Specifically considering interventions to improve adherence, only five of 14 randomized controlled trials were able to demonstrate improvements in adherence through unidimensional approaches. All nine of the case studies/series demonstrated a positive impact on adherence, eight of which described a personalized multidimensional approach. A lack of consensus around defining, measuring, and quantifying adherence with compression stockings was identified, resulting in wide variation in reported adherence rates. Conclusion Inconsistency in the definition and measurement of adherence limits meaningful interpretation of the literature. No individual intervention has consistently demonstrated improved adherence. Multidimensional interventions show promise but require further investigation with high-quality trials. Improving adherence appears to improve health outcomes in VLU /CVI populations but there is a lack of information directly linking improved adherence with cost outcomes. Trial Registration Open Science Framework: ACTRN12620000544976p.

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“…Dato il trend demografico della popolazione, la tendenza sarà quella di avere un numero crescente di pazienti affetti da tale patologia. [6][7][8] L'ulcera vascolare venosa degli arti inferiori si caratterizza per una guarigione lenta e per l'alto tasso di ricorrenza; ciò giustifica i costi sanitari e sociali, spesso, significativamente elevati. 6,8,9 La stima del tasso di recidiva delle ulcere degli arti inferiori varia dal 67% all'80%.…”

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“…[6][7][8] L'ulcera vascolare venosa degli arti inferiori si caratterizza per una guarigione lenta e per l'alto tasso di ricorrenza; ciò giustifica i costi sanitari e sociali, spesso, significativamente elevati. 6,8,9 La stima del tasso di recidiva delle ulcere degli arti inferiori varia dal 67% all'80%. L'appropriatezza e l'efficacia del percorso di cura, quindi, passano attraverso l'adeguato trattamento delle lesioni, l'intervento tempestivo sullo stile di vita e la correzione dei fattori eziologici sottostanti.…”

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<em>Empowerment</em> e cura centrata sulla persona: un progetto d’educazione terapeutica dedicato al paziente affetto da ulcere venose. Studio p

Feliziani¹,

Dichiara²,

Faccenda

et al. 2021

Ital J Wound Care

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Il progetto ha previsto lo sviluppo, la validazione e la sperimentazione di uno strumento formativo cartaceo dedicato al paziente seguito presso l’ambulatorio infermieristico per ulcere venose dell’arto inferiore. Un infermiere esperto in wound care ha progettato e, in seguito, sottoposto a validazione da parte di un team multiprofessionale un questionario composto da 5 domande concernenti la consapevolezza di malattia, la necessità di essere sottoposti a terapia e la verifica delle conoscenze di alcuni basilari concetti di fisiopatologia. Il questionario è stato somministrato ai pazienti arruolati prima e dopo l’intervento formativo attuato, al fine di testarne l’efficacia (studio pre-post test senza gruppo di controllo). L’analisi dell’efficacia dell’intervento formativo è stata effettuata testando la variazione della media dei punteggi pre (Pre-I) e post intervento (Post-I). Risultati: in base all’analisi statistica effettuata è possibile ritenere l’intervento formativo efficace per il campione selezionato con un buon livello di significatività (p<0,001): media dei punteggi Pre-I 6,22 (95% IC 5,22-7,21) e media Post-I 10,83 (95% IC 10,59-11,06). In linea con quanto presente in letteratura scientifica, lo studio condotto ha permesso all’infermiere esperto in wound care di sperimentare l’effetto della personalizzazione dell’intervento di cura e dell’empowerment sull’outcome. L’intervento formativo, così strutturato, pur risultando perfettibile, rappresenta un importante punto di partenza per ulteriori sviluppi futuri.

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Case study: A unique approach to compliance in a patient with venous ulcers

Cited by 6 publications

References 4 publications

Degradation of eschar from venous leg ulcers using a recombinant chymotrypsin from Lucilia sericata

Degradation of eschar from venous leg ulcers using a recombinant chymotrypsin from Lucilia sericata

Improving Adherence to Wearing Compression Stockings for Chronic Venous Insufficiency and Venous Leg Ulcers: A Scoping Review

<em>Empowerment</em> e cura centrata sulla persona: un progetto d’educazione terapeutica dedicato al paziente affetto da ulcere venose. Studio p

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