Case review and consideration for imaging and work evaluation of the pregnant bariatric patient

Altieri, Maria S.; Telem, Dana A.; Kim, Pamela; Gracia, Gerald; Pryor, Aurora D.

doi:10.1016/j.soard.2014.09.025

Cited by 10 publications

(4 citation statements)

References 26 publications

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“…Similar treatment delays have been reported for intestinal obstruction in pregnancy resulting from other causes (eg, volvulus, intussusception). 7,28 Early diagnosis is further complicated by a lack of striking clinical or laboratory findings in a majority of cases and a sensitivity of computed tomography and MRI of only 75%. Moreover, in some cases, care providers were reticent to use imaging as a result of the presence of the pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Internal Herniation in Pregnancy After Gastric Bypass

Vannevel

Jans

Bialecka

et al. 2016

Obstetrics &Amp; Gynecology

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Section: Discussionmentioning

confidence: 99%

Internal Herniation in Pregnancy After Gastric Bypass

Vannevel

Jans

Bialecka

et al. 2016

Obstetrics &Amp; Gynecology

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“…Platinum-based chemotherapy was shown to be effective for treating advanced NSCLC. However, in many patients, this initial response to cisplatin soon disappears and chemoresistance emerges, resulting in patient death and the poor 5-year survival rates 40. Resistance to cisplatin has become a major clinical challenge in the treatment of NSCLC.…”

Section: Discussionmentioning

confidence: 99%

HOXB13 networking with ABCG1/EZH2/Slug mediates metastasis and confers resistance to cisplatin in lung adenocarcinoma patients

Zhan¹,

Wang²,

Li³

et al. 2019

Theranostics

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Rationale: Distant metastasis and chemoresistance are the major causes of short survival after initial chemotherapy in lung adenocarcinoma patients. However, the underlying mechanisms remain elusive. Our pilot study identified high expression of the homeodomain transcription factor HOXB13 in chemoresistant lung adenocarcinomas. We aimed to investigate the role of HOXB13 in mediating lung adenocarcinoma chemoresistance. Methods: Immunohistochemistry assays were employed to assess HOXB13 protein levels in 148 non-small cell lung cancer patients. The role of HOXB13 in lung adenocarcinoma progression and resistance to cisplatin therapy was analyzed in cells, xenografted mice, and patient-derived xenografts. Needle biopsies from 15 lung adenocarcinoma patients who were resistant to cisplatin and paclitaxel therapies were analyzed for HOXB13 and EZH2 protein levels using immunohistochemistry. Results: High expression of HOXB13 observed in 17.8% of the lung adenocarcinoma patients in this study promoted cancer progression and predicted poor prognosis. HOXB13 upregulated an array of metastasis- and drug-resistance-related genes, including ABCG1, EZH2, and Slug, by directly binding to their promoters. Cisplatin induced HOXB13 expression in lung adenocarcinoma cells, and patient-derived xenografts and depletion of ABCG1 enhanced the sensitivity of lung adenocarcinoma cells to cisplatin therapy. Our results suggest that determining the combined expression of HOXB13 and its target genes can predict patient outcomes. Conclusions: A cisplatin-HOXB13-ABCG1/EZH2/Slug network may account for a novel mechanism underlying cisplatin resistance and metastasis after chemotherapy. Determining the levels of HOXB13 and its target genes from needle biopsy specimens may help predict the sensitivity of lung adenocarcinoma patients to platinum-based chemotherapy and patient outcomes.

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“…Among patients with IH, one patient had extensive bowel resection resulting in short bowel syndrome in the series by Vannevel et al (82) , one had extensive bowel necrosis and died in the series by Andreasen et al (86) , and one had bowel resection in the series by Santulli et al (91) . Adverse fetal outcomes included: I)1 case of preterm rupture of membranes, grade II intraventricular hemorrhage, grade II retinopathy of prematurity (ROP), and sepsis reported by Vannevel et al (82) , II) 1 case of preterm birth at 30 weeks of a baby with lip cleft palate and intestinal malformation, 3 weeks after laparoscopy for IH reported by Gudbrand et al (83) , III) 1 case of preterm delivery at 28 weeks, complicated by respiratory distress and bowel perforation requiring loop ileostomy and reanastomosis before discharge reported by Altieri et al (84) .…”

Section: Maternal and Fetal Outcomesmentioning

confidence: 98%

“…Systematic search process is showed in Figure 1. Sixty-eight studies reporting data on surgical complications in pregnant women with previous history of bariatric procedures were retrieved with a systematic literature search (33,34, (81)(82)(83)(84)(85)(86)(87)(88)(89)(90)(91)(92)(93) . The included studies were published between 1988 and 2018, and they were all retrospective.…”

Section: Study Selectionmentioning

confidence: 99%