Case report of intra-osseous fibroma: a study on odontogenic and desmoplastic fibromas with a review of the literature

Abstract

Intra-osseous fibromas of the jaw are classified by origin. Intra-osseous odontogenic fibromas have odontogenic epithelia, while desmoplastic fibromas do not. However, it is often difficult to determine the odontogenic origin for central fibromas. Three subjects with a diagnosis of intra-osseous fibroma were examined. Case 1 was a 35-year-old man found to have a panoramic radiograph from the right premolar to the mandibular ramus in the mandible that exhibited multilocular radiolucency. Within the radiolucency, small-radioopaque bodies were observed. Case 2 was a 13-year-old female, in whom a panoramic radiograph from the left premolar to the molar in the mandible showed multilocular radiolucency. Case 3 was a 51-yearold female who exhibited a heart-shaped radiolucency in the panoramic radiograph of the left first molar area in the mandible. We also reviewed the literature for previously reported cases of intra-osseous odontogenic and desmoplastic fibroma. In 64 cases of intra-osseous odontogenic fibroma and 68 cases of desmoplastic fibroma we extracted data on age, sex, location, and radiographic findings. Based on the analysis of the reported literature cases, re-evaluation of the patients in our study revealed that case 1 could be classified as desmoplastic fibroma, while cases 2 and 3 were intra-osseous odontogenic fibromas. (J. Oral Sci. 47, [149][150][151][152][153][154][155][156][157] 2005)

Epithelium Rich Type Central Odontogenic Fibroma in Maxilla a Case Report and Review of Literature

“…Desmoplastic fibroma is found to affect mainly the mandible with high tendency for bone expansion unlike COF that have equidistance in mandible and maxilla. Radiographically, COF appear to have varying characteristics divided between unilocular and multilocular appearance with incidence of root resorption compared to desmoplastic type which have three more time to be multilocular appearance [28]. In conclusion, differentiation between both lesions is still difficult but one can consider the diagnosis of COF if it doesn't clearly shows features of desmoplastic fibroma [24].…”

“…It shares many features with soft tissue desmoids tumors and fibromatosis. It is an infiltrative to the surrounding while COF do not and requires wide resection margins rather than ostectomy for treating COF [28]. Ibarguren et al [29] in 2006 reported a case of locally aggressive, large COF (desmoplastic) variant occupying the right half of the mandible pushing the third molar up to the coronoid, which was involved by an inflammatory cyst.…”

“…Based on the presence or absence of odontogenic epithelium, intra-osseous fibroma can be classified into odontogenic fibroma and non-odontogenic fibroma (desmoplastic fibroma) [28]. It is very difficult to distinguish microscopically between them especially in the absence of odontogenic epithelium.…”

Fibromyxoma of mandibular gingiva: a case study

“…The presence of calcifications found in the histopathological examination was also observed by Miettinen et al [12]. These calcifications are specific characteristics of the fibromyxomas and are essential for the differential diagnosis [11,16].…”

Desmoplastic fibroma in the proximal femur: A case report with long-term follow-up

“…The most common location is the mandible, followed by the extremities, head and spine. The incidence is estimated at 0.06% among all bone tumors and 0.3% among benign bone tumors (1)(2)(3)(4). Desmoplastic fibroma of the bone occurs most often in the first three decades of life and is found equally among men and women (5).…”