Desmoplastic fibroma in the proximal femur: A case report with long-term follow-up

Abstract

Abstract. Desmoplastic fibroma of the bone is an extremely rare primary benign tumor. The present study reports a case of desmoplastic fibroma of the bone with the longest published follow-up. A 21-year-old female presented to The First Hospital of Jilin University (Changchun, Jilin, China) with thigh pain. Radiography demonstrated a lytic expansile lesion in the proximal femur. Curettage was performed, followed by use of an allogeneic graft. One month later, the patient suffered a pathological fracture and was treated with an open reduction and internal fixation. There was no recurrence of the tumor over a 28-year follow-up period. In conclusion, desmoplastic fibroma in the proximal femur is rare and an intralesional resection is strongly recommended to prevent recurrence. The disease may be misdiagnosed as a bone cyst, so the diagnosis should be confirmed with a histological examination.

Distal Femoral Replacement as a Salvage Treatment After Desmoplastic Fibroma Resection

“…However, despite better curative rates with wide tumor resection, the functional prognosis could be compromised when dealing with massive lesions [ 8 , 9 ]. In those patients, conservative surgery (ie, curettage) persists as a treatment option if surgical resection would translate into significant morbidity or loss of functionality [ 4 , 9 , 10 , 16 ]. Ultimately, radiation therapy could reduce the pain and limit tumor progression in inoperable tumors [ 6 ].…”

Desmoplastic fibroma of bone: Amorphological and immunehistochemical characterization

“…Desmoplastic fibroma (DF) of bone is an infrequent and locally aggressive benign neoplasm, representing 0.06% of all bone neoplasms and 0.3% of benign neoplasms in this location [1]. In pediatric population, the occurrence of this entity is lowest than 1% of bone neoplasms.…”