Case Report and Literature Review of Nodular Hidradenoma, a Rare Adnexal Tumor That Mimics Breast Carcinoma, in a 20-Year-Old Woman

Abstract

Nodular hidradenoma is an uncommon cutaneous adnexal tumor arising from sweat glands. In the skin, it usually presents as a solitary dermal nodule; excision is curative in most cases. In rare instances, it may present as a breast mass and can mimic breast carcinoma clinically and radiologically, causing diagnostic dilemmas for the treating physician and pathologist. Herein, we discuss a case of nodular hidradenoma in a 20-year-old Hispanic woman as a rapidly growing mass in the breast that mimicked breast carcinoma. We discuss the rare presentation of this uncommon tumor and the differential diagnosis of this entity, as well as the results of our literature review on the topic.

Nodular hidradenoma: A worrisome mass lesion

“…Nodular hidradenoma is a rare disease so, it is difficult to make a diagnosis preoperatively. [1][2][3][4] Clinical, radiological and operative findings are not enough to define it accurately therefore histopathology helps to make a definitive diagnosis. [6][7][8][9] A few cases of nodular hidradenoma have been reported in past literature.…”

“…[6][7][8][9] A few cases of nodular hidradenoma have been reported in past literature. [1][2][3][4][5][6][7][8][9]…”

“…Nodular hidradenoma is identified as tumor of skin that takes its origin from sweat gland. 1,2 Its common locations are scalp, face, neck, shoulders, breast and upper limbs. 3,4 This tumor is frequently observed in elderly females.…”

Clear Cell Hidradenoma of the Breast Diagnosed on a Core Needle Biopsy: A case report and review of the literature

“…The most common presenting complaint is a painless breast mass but some patients can also present with nipple discharge, bluish discolouration of the overlying skin or ulceration. 5,26 CCH can easily be misdiagnosed preoperatively as a carcinoma of the breast.…”

Pedunculated Tumor on the Posterior Neck

“…8 Histopathology shows clusters of atypical, nucleated clear cells surrounded by chicken wire vasculature. 8,9 Verruca vulgaris is caused by human papillomavirus and most commonly occurs on the hands and feet. It presents as a pink to white, sessile lesion with a verrucous surface and exophytic growths.…”