Case report 713

Juxtacortical Chondromyxoid Fibroma of Bone: A Unique Variant

“…In addition to individual case reports, [1][2][3]5,6,8,[11][12][13][14]16,20,[23][24][25]27,30,31,33,34,36,41,[46][47][48]50 there have been multiple reviews of this lesion in which the experience ranging from several to many patients has been summarized. 7,9,10,17,21,29,37,52,55 In its typical presentation, CMF occurs in the intramedullary portion of the metaphysis of long bones in the second to third decade of life.…”

Chondromyxoid Fibroma

“…CMFs arise most frequently in the metaphysis of long tubular bones; however, they may involve virtually any bone of the body (5)(6)(7)(8)(9)(10). Roughly 75% of cases involve the lower extremity, with 40% involving the knee; nonetheless, some 17% to 20% occur in the foot, making this the second most common location (11,12). A number of authors have opined that the metatarsals are the most commonly affected (6,7,13).…”

“…Occasionally, the tumor may be asymptomatic and discovered on routine radiographs; however, pathologic fracture is also a distinct possibility if development has gone unnoticed. Most cases are found in the second and third decades of life and demonstrate a slight bias toward male sex with a prevalence (male:female) of 1.5:1 (3,4,12,14,17).…”

“…Advanced imaging modalities including computed tomography, magnetic resonance imaging (MRI), angiography, and bone scans have all been used as adjuncts in diagnosis (3,12,14,17). In addition to the aforementioned radiographic features, specific findings discerned from MRI and computed tomography include excellent spatial resolution and delineation of the anatomic boundaries of the tumor.…”

“…The MRI features associated with CMF are varied, and there is considerable overlap with other neoplasms. It has been described as homogenous and isointense with muscle on T1-weighted images but hyperintense on T2 images (12,14,20). In addition, peritumoral marrow edema may be identified.…”