Case 22-1987

Cabot, Richard C.; Scully, Robert E.; Mark, Eugene J.; McNeely, William F.; McNeely, Betty U.

doi:10.1056/nejm198705283162208

N Engl J Med

1987

DOI: 10.1056/nejm198705283162208

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Case 22-1987

Richard C. Cabot¹,

Robert E. Scully²,

Eugene J. Mark³

et al.

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Cited by 9 publications

References 34 publications

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Primary lymphoma of the heart. Prolonged survival with early systemic therapy in a patient

Nand¹,

Mullen²,

Lonchyna

et al. 1991

Cancer

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Primary lymphoma of the heart is an uncommon malignancy usually recognized at autopsy or fatal within a few weeks of diagnosis. Recently, it was reported in patients with acquired immune deficiency syndrome. A patient with diffuse large cell lymphoma of the heart is reported who had chest pain and rapidly evolving cardiac arrhythmias. The human immune deficiency virus antibody test was negative. Because of an aggressive diagnostic approach, therapy with cyclophosphamide, doxorubicin, vincristine, and prednisone was started on the third day after diagnosis. The patient has survived 18 months with an objective response. To the authors' knowledge, this is the longest reported survival in primary cardiac lymphoma. The diagnosis in this patient was aided by excellent tumor delineation by nuclear magnetic resonance scanning. The authors believe that better survival in this patient was a result of prompt diagnosis and treatment because the behavior of the lymphoma was similar to aggressive lymphomas arising elsewhere. Cancer 68:2289–2292, 1991.

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Primary lymphoma of the heart. Prolonged survival with early systemic therapy in a patient

Nand¹,

Mullen²,

Lonchyna

et al. 1991

Cancer

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Primary lymphoma of the pericardium: Report on a „Cured”︁ case and review of the literature

Pavlidis

Elisaf

Bai

et al. 1994

Med. Pediatr. Oncol.

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This report describes a 62-year-old man with a primary diffuse, immunohistochemically proven B-cell lymphoma of large non-cleaved cell (centroblastic) type of the pericardium. The patient responded completely to systemic chemotherapy and remains free of disease 30 months after diagnosis. The use of non-cardiotoxic drugs in divided doses as initial treatment is emphasized. In addition, the authors reviewed the literature of the last decade regarding the management and outcome of patients with primary cardiac lymphomas.

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Malignant lymphoma with primary cardiac manifestations: A case report

Stein¹,

Zyssman

Kantor

et al. 1994

Med. Pediatr. Oncol.

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This case report describes a 29-year-old black patient presenting with right heart failure secondary to massive lymphomatous cardiac involvement. Additional sites of involvement included mesenteric lymph nodes and the small bowel. Malignant lymphoma with primary cardiac manifestations is very rare and follows an aggressive course. The importance of early diagnosis and commencement of immediate therapy is emphasized.

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Case 22-1987

Cited by 9 publications

References 34 publications

Primary lymphoma of the heart. Prolonged survival with early systemic therapy in a patient

Primary lymphoma of the heart. Prolonged survival with early systemic therapy in a patient

Primary lymphoma of the pericardium: Report on a „Cured”︁ case and review of the literature

Malignant lymphoma with primary cardiac manifestations: A case report

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