"Cascade"- and "Nonskid-Chain-like" Syntheses of Molecular Cavity Topologies

Buhleier, E.; Wehner, W.; Vögtle, Fritz

doi:10.1055/s-1978-24702

Cited by 1,302 publications

(937 citation statements)

References 0 publications

Supporting

Mentioning

902

Contrasting

Unclassified

Order By: Relevance

“…Moreover, the chemical environments of protons H 22 in P 1 and H 27 in P 2 (for numbering, see Scheme 1), were strongly modified and led to a significant downfield shift of the associated signals (0.46 and 0.48 ppm, respectively). In their 13 C{ 1 H} NMR spectra, an upfield shift was also observed for the signals of carbons C 21 in P 1 (4.87 ppm) and C 26 in P 2 (5.18 ppm). All chemical shifts were consistent with the formation of P 1 and P 2 and full assignments are given in the Experimental Section.…”

Section: Resultsmentioning

confidence: 92%

See 1 more Smart Citation

Encapsulation of Pyrene‐Functionalized Poly(benzyl ether) Dendrons into a Water‐Soluble Organometallic Cage

Barry

Zava

Deschenaux

et al. 2011

Chemistry An Asian Journal

View full text Add to dashboard Cite

Two generations of lipophilic pyrenyl functionalized poly(benzyl ether) dendrimers (P1 and P2) have been synthesized. The thermal properties of the two functionalized dendrimers have been investigated, and the pyrenyl group of the dendritic molecules encapsulated in the arene–ruthenium metalla‐cage, [Ru6(p‐cymene)6(tpt)2(donq)3]6+ ([1]6+) (tpt=2,4,6‐tri(pyridin‐4‐yl)‐1,3,5‐triazine; donq=5,8‐dioxydo‐1,4‐naphthoquinonato). The host–guest properties of [P1⊂1]6+ and [P2⊂1]6+ were studied in solution by NMR and UV/Vis spectroscopic methods, thus allowing the determination of the affinity constants. Moreover, the cytotoxicity of these water‐soluble host–guest systems was evaluated on human ovarian cancer cells.

show abstract

Section: Resultsmentioning

confidence: 92%

“…10 and H 10' ), 1.28 (m, 84 H, H aliphatic and CHA C H T U N G T R E N N U N G (CH 3 ) 2 ), 0.88 ppm (m, 9 H, H 1 and H 1' ). 13 …”

mentioning

confidence: 99%

Encapsulation of Pyrene‐Functionalized Poly(benzyl ether) Dendrons into a Water‐Soluble Organometallic Cage

Barry

Zava

Deschenaux

et al. 2011

Chemistry An Asian Journal

View full text Add to dashboard Cite

show abstract

“…L'idée de (( ramification )) est présenteà toutes leséchelles dans la nature, de la ramure des arbres a la structure des neurones mais pasà l'échelle moléculaire. Ce concept a d'abordété développé par Flory (1936Flory ( , 1940 au milieu du siècle précédent, avant que Vögtle le concrétise en 1978 (Buhleier et al, 1978), puis que Tomalia crée le mot (( dendrimer )) (Tomalia et al, 1985).…”

unclassified

Article retiré – Utilisation de dendrimères pour une nanomédecine innovatrice

Majoral

2013

Biologie Aujourd'hui

View full text Add to dashboard Cite

Reçu le 15 octobre 2012Résumé -Les dendrimères et plus particulièrement les dendrimères phosphorés présentent une grande variété d'applications dans de nombreux domaines : biologie, médecine mais aussi science des matériaux ou encore catalyse. Cet article décrit succinctement quelques-unes des applications des dendrimères phosphorés en nanomédecine. Mots clés : Dendrimères / phosphore / nanomédecine / imagerie / applications biologiques Abstract -Using dendrimers for an innovative nanomedicine.Dendrimers and more particularly phosphorus containing dendrimers are useful nanoobjects for a variety of applications ranging from biology, medicine and materials sciences to catalysis. This manuscript reports briefly some applications of phosphorus dendrimers in the field of nanomedicine.

show abstract

“…Multivalent dendrimers are attracting a great deal of interest for applications in biomedical diagnostics [27][28][29][30], pharmacology / drug delivery [31,32] [33], cancer research [34], and nanomedicine [35]. Their use in research is still unabated now, 30 years after their first reported synthesis by Vogtle [36].…”

mentioning

confidence: 99%

A comparison of mono and multivalent linkers and their effect on the colloidal stability of nanoparticle and immunoassays performance

Gubala

Guével

Nooney

et al. 2010

Talanta

View full text Add to dashboard Cite

When designing devices for biomedical diagnostics, increasing the signal to noise ratio is often critical for achieving clinically relevant sensitivity and limits of detection (LOD). In antibodybased assays, the measured signal can be amplified through the replacement of molecular fluorophores with doped nanoparticles (NP). However, the benefits of using NPs can only be realized if the NPs are coated efficiently with detection antibody, have good colloidal stability and the ratio of specific to non-specific binding (NSB) is high enough. The main focus of this paper is on the optimization of the bioconjugation protocol for antibody labeling of NPs leading to improved assay performance. Two types of linkers were used: monovalent linkers (glutaraldehyde; sulfo-SMCC; and sulfo-SIAB), and three generations of dendrimers endowed with multivalent carboxylic functionality. Overall, the NP-IgG conjugates prepared using multivalent linkers showed a significantly lower LOD and higher sensitivity than their homo-or hetero-functional counterparts. The multivalent dendrimers also improved NP stability and reduced aggregation. Moreover, the dendrimers showed a higher reactivity with biological material, a feature that could significantly reduce the cost of high-throughput biodiagnostics tests. Introduction:

show abstract

"Cascade"- and "Nonskid-Chain-like" Syntheses of Molecular Cavity Topologies

Cited by 1,302 publications

References 0 publications

Encapsulation of Pyrene‐Functionalized Poly(benzyl ether) Dendrons into a Water‐Soluble Organometallic Cage

Encapsulation of Pyrene‐Functionalized Poly(benzyl ether) Dendrons into a Water‐Soluble Organometallic Cage

Article retiré – Utilisation de dendrimères pour une nanomédecine innovatrice

A comparison of mono and multivalent linkers and their effect on the colloidal stability of nanoparticle and immunoassays performance

Contact Info

Product

Resources

About