Carotid Intima-Media Thickness in Diabetics and Hypertensive Patients

Gómez‐Marcos, Manuel A.; Rodríguez‐Sánchez, Emiliano; Patino-Alonso, María C.; Magallón-Botaya, Rosa; Martínez‐Vizcaíno, Vicente; Sánchez, Luz Pérez

doi:10.1016/j.rec.2010.10.025

Cited by 9 publications

(13 citation statements)

References 11 publications

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“…In view of the very high incidence of type 2 and the reported prevalence of atherosclerotic vascular disease in this category of diabetics in our environment [17]. This study was aimed at evaluating the carotid intima-media thickness in type 2 diabetic and correlations with any clinical/laboratory parameters.…”

Section: Introductionmentioning

confidence: 99%

Relationship between Carotid Intima-Media Thickness and Diabetes Clinical Risk Factors among Normotensive Type 2 Diabetes Mellitus among Native Black African Population

Okafor¹,

Adekanmi²,

Atalabi³

2018

IJCM

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Background: Type 2 diabetes mellitus is frequently associated with atherosclerosis with changes in the thickness of the intima-media of carotid arteries which causes increased risk of cardiovascular diseases. Cardiovascular disease is a major cause of morbidity and mortality in this group of patients. The carotid artery reflects the degree of atherosclerosis in the various vessels especially coronary arteries. Measurement of the carotid artery thickness with real time, relatively cheap and non-invasive ultrasonography method is used in monitoring atherosclerotic disease progression and response to treatment. This study is aimed at ultrasonographic evaluation of the carotid intima-media thickness (CIMT) in adult Type 2 Diabetic patients compared to non-diabetic healthy controls matched for age, gender and body mass index (BMI). And to also determine its association if any with selected clinical factors among a native Black African population. Methodology: This was a prospective case control study involving 54 adult type 2 diabetics and 54 adult non-diabetic controls. CIMT was measured at 3 segments of the extracranial carotid arteries by a 7.5-10 MHz linear transducer of a portable Mindray M5 ultrasound machine. Results: Among the native black African population studied, there was significant difference in CIMT of adult type 2 diabetics compared to healthy non-diabetics adults (p value = 0.012 and 0.001 on the right and left respectively). The mean carotid intima-media thickness in diabetics was 0.81 mm and 0.85 mm, while in non-diabetics it was 0.74 mm and 0.75 mm on the right and left respectively. The presence of diabetes showed independent positive correlation with CIMT (beta: 0.24, p value = 0.004). Age (beta: 0.30, p value = 0.001) and plasma cholesterol level (beta: 0.30, p value = 0.013

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Section: Introductionmentioning

confidence: 99%

Relationship between Carotid Intima-Media Thickness and Diabetes Clinical Risk Factors among Normotensive Type 2 Diabetes Mellitus among Native Black African Population

Okafor¹,

Adekanmi²,

Atalabi³

2018

IJCM

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“…The study of Gomez mancos MA et al supports our study. 18 Regarding thickness of common carotid artery on both sides, it is high in both groups but it is significantly higher in diabetes group than hypertensive group. Which supported by the work of E.J.…”

Section: Discussionmentioning

confidence: 89%

Ultrasonographic Evaluation of Intima Media Thickness of Carotid Arteries among Hypertensive and Hypertensive with Diabetes Mellitus

Ramana¹,

Kumar²

2019

IJCMSR

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How to cite this article: Kada Venkata Ramana, T. Rajesh Kumar. Ultrasonographic evaluation of intima media thickness of carotid arteries among hypertensive and hypertensive with diabetes mellitus. International Journal of Contemporary Medicine Surgery and Radiology. 2019;4(3):C158-C161. was also measured. HBA1 C was also measured on all patients. For measurement of carotid in time media thickness we used Philips clear view 650 ultra sound with linear probe having 8MH 8 solution. Unpaired T test and chi square test was used for comparison of data and P value less than 0.05 were considered significant. Result: Thickness of Rt. Common carotid in group H was 0.716+ 0.03mm and in group HD it was 0.8495+0.07 having P value 0.0001.Thickness of carotid intima and media was 0.723+ 0.183 in group H in left carotid artery. But left carotid intima media thickness in group HD was 0.8495+ 0.07mm. The P value was 0.0001. The mean of carotid intima media thickness of right internal carotid artery in group H was 0.642+ 0.432 mm and the P value was 0.007. Conclusion: CIMT was significantly higher in patient suffering from diabetes mellitus and hypertension then hypertension alone. This indicate that diabetes along with hypertension accelerate the atherosclerosis process.

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“…Gomez-Marcos et al [15] reported that the correlation coe cient for healthy subjects was 0.706 and this coe cient was measured by Homma et al [16] as 0.84. We have also found a linear tendency between age and IMT in this study, as well correlation coe cient was computed as 0.87.…”

Section: Intima Growth Ratementioning

confidence: 93%

“…For every 0.1 mm increase in carotid IMT, the relative risk of ischemic heart disease increases by 15% [15]. Therefore, the presented model of inti- mal thickening, which can be applied to people with di erent transmural pressure, provides advantageous information to predict atherosclerosis susceptibility in di erent conditions.…”

Section: Intima Growth Ratementioning

confidence: 99%

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Eeffcts of hypertension on Intima-Media Thickness (IMT); application to a human carotid artery

et al. 2016

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Abstract. A vast number of deaths in the world have been attributed to atherosclerosis.The prominent aim of this study is proposing an accurate and simple model to investigate the process of arterial wall thickening. In order to investigate LDL (Low Density Lipoprotein) accumulation in arterial wall, a four layer model for arterial wall consisting of endothelium, intima, IEL, and media is presented. All layers are treated as homogenous porous media. This model has been solved both numerically and analytically. Obtained accumulated LDL in the intima is used to calculate oxidized LDL ux. Also, the presented model and clinical data are used to prepare the growth model for arterial wall. Furthermore, the e ect of hypertension on ltration velocity and rate of wall thickening has been studied which is in consistent with experimental data. Results show that the average rates of intima thickening of hypertensive patients with 120 mmHg and 160 mmHg transmural pressure are 5.87 m/year and 6.12 m/year, respectively. This rate for healthy subjects with 70 mmHg transmural pressure has been calculated 4.5 m/year. Finally, this model is applied to a carotid artery, and the maximum intimal growth rate for people with 70 mmHg, 120 mmHg and 160 mmHg transmural pressure is calculated 4.68 m/year, 6.28 m/year, and 6.67 m/year, respectively.

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Carotid Intima-Media Thickness in Diabetics and Hypertensive Patients

Cited by 9 publications

References 11 publications

Relationship between Carotid Intima-Media Thickness and Diabetes Clinical Risk Factors among Normotensive Type 2 Diabetes Mellitus among Native Black African Population

Relationship between Carotid Intima-Media Thickness and Diabetes Clinical Risk Factors among Normotensive Type 2 Diabetes Mellitus among Native Black African Population

Ultrasonographic Evaluation of Intima Media Thickness of Carotid Arteries among Hypertensive and Hypertensive with Diabetes Mellitus

Eeffcts of hypertension on Intima-Media Thickness (IMT); application to a human carotid artery

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