Carotid atherosclerosis, intima media thickness and risk factors—an analysis of 1781 asymptomatic subjects in Taiwan

Sun, Yu; Lin, Cheng-Huai; Lu, Chien-Jung; Yip, Ping-Keung; Chen, Rong-Chi

doi:10.1016/s0021-9150(02)00017-5

Cited by 106 publications

(73 citation statements)

References 22 publications

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“…Carotid ultrasound examination of CA has been conducted in several population studies10, 11, 12; however, the epidemiology of carotid lesions in China may be different from other regions because of differences in ethnic and racial groups. Furthermore, data are limited in urban and rural areas, and there have been no nationally representative studies on the prevalence of CA in China.…”

Section: Introductionmentioning

confidence: 99%

Carotid Atherosclerosis Detected by Ultrasonography: A National Cross‐Sectional Study

Wang¹,

Li²,

Song

et al. 2018

JAHA

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BackgroundCarotid atherosclerosis (CA) is a reflector of generalized atherosclerosis that is associated with systemic vascular disease. Data are limited on the epidemiology of carotid lesions in a large, nationally representative population sample. We aimed to evaluate the prevalence of CA detected by carotid ultrasonography and related risk factors based on a national survey in China.Methods and ResultsA total of 107 095 residents aged ≥40 years from the China National Stroke Prevention Project underwent carotid ultrasound examination. Participants with carotid endarterectomy or carotid stenting and those with stroke or coronary heart disease were excluded. Data from 84 880 participants were included in the analysis. CA was defined as increased intima–media thickness (IMT) ≥1 mm or presence of plaques. Of the 84 880 participants, 46.4% were men, and the mean age was 60.7±10.3 years. The standardized prevalence of CA was 36.2% overall, increased with age, and was higher in men than in women. Prevalence of CA was higher among participants living in rural areas than in urban areas. Approximately 26.5% of participants had increased IMT, and 13.9% presented plaques. There was an age‐related increase in participants with increased IMT, plaque presence, and stenosis. In multiple logistic regression analysis, older age, male sex, residence in rural areas, smoking, alcohol consumption, physical inactivity, obesity, hypertension, diabetes mellitus, and dyslipidemia were associated with CA.Conclusions CA was highly prevalent in a middle‐aged and older Chinese population. This result shows the potential clinical importance of focusing on primary prevention of atherosclerosis progression.

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Section: Introductionmentioning

confidence: 99%

Carotid Atherosclerosis Detected by Ultrasonography: A National Cross‐Sectional Study

Wang¹,

Li²,

Song

et al. 2018

JAHA

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“…Moreover, the IMT measurements of this study are very close to the studies in [7] and [12] as tabulated in Table 1. There were only two studies [7], and [8] that showed significant differences between the left and the right sides for the normal group. Significant differences between the left and the right sides were shown for the CVD group for this study as well as in [12] and [30]; in contrast to the findings of the study in [10] that showed no significant differences between the two sides (see Table 1).…”

Section: Discussionmentioning

confidence: 99%

A comparison of ultrasound intima media thickness measurements of the left and right common carotid artery

Loizou

Pattichis

Georghiou³

et al. 2013

13th IEEE International Conference on BioInformatics and BioEngineering

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The intima-media thickness (IMT) of the common carotid artery (CCA) is an established indicator of cardiovascular disease (CVD). There have been reports about the difference between the left and the right sides of the CCA IMT and their relation with CVD. In this paper, we propose an automated system based on image normalization, speckle reduction filtering, and snakes segmentation, for segmenting the CCA, perform IMT measurements, and provide the differences between the left and the right sides. The study was performed on 1104 longitudinal-section ultrasound images acquired from 568 men and 536 women out of which 125 had cardiovascular symptoms (CVD). A cardiovascular expert manually delineated the IMT for the normal and the CVD groups. The corresponding (normal versus CVD) IMT mean ± standard deviation values for the left and the right sides were 0.74 ± 0.24 versus 0.87 ± 0.24 mm and 0.70 ± 0.17 versus 0.80 ± 0.18 mm, respectively. The main findings of this paper can be summarized as follows: 1) there was no significant difference between the CCA left side IMT and the right side IMT. These findings suggest that the measurement of the CCA IMT on one side only is needed for the normal group (and this is in agreement with other studies); 2) there were statistical significant differences for the IMT measurements between the normal group and the CVD group for both the left and the right sides; 3) there was an increasing linear relationship of the left and the right IMT measurements with age for the normal group; and to a lesser extend for the CVD group; 4) no statistical significant differences were found between the manual and the automated IMT measurements for both sides; and 5) the best result for classification disease modeling, using support vector machines, to discriminate between the normal and the CVD groups was a 64% ± 3.5% correct classifications score when using both the left and the right IMT automated measurements. Further research is required for estimating differences and similarities between left and right intima media complex structure and morphology and their variability with texture features for differentiating between the normal and the CVD group. INDEX TERMSB-mode, ultrasound imaging, common carotid artery, intima media thickness, IMT, cardiovascular disease.

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“…Th ickness increases with age 26 . In addition to the change with age, IMT also increases with earlier plaque formation; therefore, IMT measurement is used as the sign of cardiovascular risk in many clinical settings 27 and the carotid IMT is a strong predictor of cardiovascular events such as MI and stroke. In addition, increased carotid IMT is associated with HT, hyperlipidemia and cardiovascular diseases 28,29 .…”

Section: Discussionmentioning

confidence: 99%

Relation between cardiovascular disease risk factors and common carotid artery intima media thickness

Şafak¹,

Akçiçek²

2015

Kafkas J Med Sci

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Carotid atherosclerosis, intima media thickness and risk factors—an analysis of 1781 asymptomatic subjects in Taiwan

Cited by 106 publications

References 22 publications

Carotid Atherosclerosis Detected by Ultrasonography: A National Cross‐Sectional Study

Carotid Atherosclerosis Detected by Ultrasonography: A National Cross‐Sectional Study

A comparison of ultrasound intima media thickness measurements of the left and right common carotid artery

Relation between cardiovascular disease risk factors and common carotid artery intima media thickness

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