Carisolv^TM: an alternative to NaOCl in immature root canals?

Abstract

1. The ovine incisor model presents opportunities to investigate irrigation regimes under controlled ex-vivo conditions. 2.NaOCl (5%) remains the most effective irrigant for rapid debris removal in immature root canals. 3. Carisolv cleans pulp debris from the walls of immature root canals as effectively as NaOCl (1%) during static, unrefreshed wall contact for between 20 and 30 min. 4. Refreshment of NaOCl (1%) enhances its cleaning ability above that of Carisolv.

Systematic Review and Meta-Analysis of Randomized Clinical Trials on Chemomechanical Caries Removal

“…Another six studies were excluded because they utilized chemomechanical caries removal agents for other purposes not related to caries excavation, such as treatment of oral ulcers, 16 periodontal therapy, 17,18 cleaning of organic debris prior to application of pit and fissure sealants, 19 plaque removal, 20 and root canal irrigation. 21 From the remaining 31 clinical studies, three were case reports, and seven were nonrandomized clinical trials and were therefore excluded. Two clinical trials were further excluded, because they were conducted on special needs patients.…”

A Comparative Scanning Electron Microscopic Investigation of the Smear Layer after the Use of Sodium Hypochlorite Gel and Solution Forms as Root Canal Irrigants

“…However, we did not find any significant differences between NaOCl solution and gel in the three parts of the root canal walls, which shows that the use of NaOCl gel can be effective in smear layer removal and we can eliminate the side effects of NaOCl solution with the use of NaOCl gel. Other investigators such as Antonio et al (16) and Rahmann et al (17) used Carisolve (Med Team, Goteborg, Sweden) as a root canal irrigant without any significant effectiveness in smear layer removal. Carisolve is a gel form of 0.05% NaOCl that is advocated for chemomechanical removal of infected carious dentin (18).…”

Current update of chemomechanical caries removal methods

“…treatment of oral ulcers, 50 periodontal therapy, 51,52 cleaning of organic debris prior to application of pit and fissure sealants, 53 plaque removal 54 and root canal irrigation. 55 …”