“…Van Itallie et d ( 5 ) stated that preliminary studies of red cell fragility failed to show changes in the integrity of the red cell membrane, but no details were given, Lerner, Chaikoff, and Entenman (6) likewise reported the occurrence of anemia in a group of dogs given intravenous fat for prolonged periods as did Dunham and Brunschwig(7) and Collins (8). Van Itallie et d ( 5 ) stated that preliminary studies of red cell fragility failed to show changes in the integrity of the red cell membrane, but no details were given, Lerner, Chaikoff, and Entenman (6) likewise reported the occurrence of anemia in a group of dogs given intravenous fat for prolonged periods as did Dunham and Brunschwig(7) and Collins (8).…”