Caries risk in patients with thalassaemia major

Hattab, Faiez N.; Hazza'a, Abdalla M; Yassin, Othman M.; Al‐Rimawi, Halla S.

doi:10.1002/j.1875-595x.2001.tb00815.x

Cited by 30 publications

(34 citation statements)

References 13 publications

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“…Urea is secreted continuously in the range of 3-10 mM in saliva and crevicular fluids of healthy individuals [6] and is rapidly hydrolyzed by the urease enzymes of oral microflora. Existing data indirectly 4 ) in the two groups support a major role for ureolysis in plaque pH homeostasis. Elevated salivary urea and ammonia concentrations correlate with marked reductions in the extent and duration of plaque acidification following a carbohydrate challenge [9].…”

Section: Discussionmentioning

confidence: 86%

“…Previous studies [1,4,15] suggest that a higher prevalence of gingivitis would be seen in TM patients and correlate to local factors or the maxillofacial characteristics of thalassemic disease. It is well known that orthodontic problems such as crowding, extreme maxillary overjet, crossbite, and oral breathing are mainly implicated in gingival disease [8,14].…”

Section: Discussionmentioning

confidence: 99%

“…A small number of clinical studies have analyzed the status of the oral cavities in thalassemic patients, considering both dental and periodontal conditions [4,5,13,14,15]. Delayed eruption of both deciduous and permanent teeth and high frequency of caries were observed; moreover, caries disease was related to the severity of systemic disease.…”

Section: Introductionmentioning

confidence: 99%

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Oral condition, chemistry of saliva, and salivary levels of Streptococcus mutans in thalassemic patients

Lugliè

Campus

Deiola

et al. 2002

Clinical Oral Investigations

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The purpose of this investigation was to determine the oral status in a group of patients with thalassemia major (TM). Eighteen TM patients (15 M, three F) and 18 healthy controls randomly matched for age and sex were examined for dental caries using the decayed, missing, and filled teeth (DMFT) index and for oral hygiene conditions using the oral hygiene index (OHI)-S. Spontaneous saliva was collected from each subject, and the biochemical composition (calcium, phosphorous, potassium, sodium, urea) was determined. Furthermore, salivary Streptococcus mutans levels were evaluated. Statistical analysis (Student's t-test) were performed for means comparison, while independence among categorical variables was assessed using the chi(2) test. Fisher's exact test was used when expected cell values were less than 5. Dental status (DMFT index) was almost equal in the two groups (10.3 in TM vs 9.4 in controls, P=0.34). The occurrence of plaque (OHI-S 2) was higher in the control group, but no statistically significant association was observed between oral hygiene conditions in the two groups (Fisher's exact test 0.47, P=0.79). Biochemical saliva composition was very similar in the two groups; only the urea concentration was lower in TM, and this difference was statistically significant ( P=0.002). The TM patients had an increased presence of mutans streptococci at detectable levels. Our findings confirm that, although no substantial differences were found between the two observed groups, further investigations are needed to determine the theoretical risk of oral diseases in thalassemic patients.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Oral condition, chemistry of saliva, and salivary levels of Streptococcus mutans in thalassemic patients

Lugliè

Campus

Deiola

et al. 2002

Clinical Oral Investigations

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“…Generally, systemic factors can play a role in the etiology of periodontal disease; therefore most of studies focus on periodontal problems (Hattab et al, 2001; Mohammed, 2004, Al-Jobouri, 2007. Affected patients usually suffer from dentofacial anomalies, which are a condition, characterized by deviations from the accepted ideal.…”

Section: Introductionmentioning

confidence: 99%

ORAL HEALTH AND DENTOFACIAL ANOMALIES AMONG Β-Thalassemia MAJOR IN ERBIL CITY, IRAQ

Saeed¹,

Majeed²,

Тарасенко³

2010

AIP Conference Proceedings

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“…Bu anomalilerin ortaya çıkı-şında genellikle genetik yatkınlık ön plânda olup, bazı sendromlarla da ilişkilendirilmekte-dir (19).…”

Section: Discussionunclassified

Bir grup Türk popülasyonunda üçüncü molar eksikliği ile ilişkili dental anomalilerin radyografik olarak değerlendirilmesi

CANTEKİN¹

2013

Ankara Üniversitesi Diş Hekimliği Fakültesi Dergisi

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The aim of this study was to investigate the frequency of dental anomalies in a Turkish population with different patterns of third-molar agenesis, comparing them with patients without thirdmolar agenesis.A sample of 1552 patients with agenesis of at least 1 third molar was divided into 4 groups according to the third-molar agenesis pattern, and a control group of 402 patients without third-molar agenesis was randomly selected from the Erciyes University-Oral and Maxillo Facial Radiology archives. Panoramic radiographs were used to determine the associated dental anomalies, such as hypodontia, hyperdontia, impaction, dilaceration, microdontia, ectopic eruption, transposition, and transmigration. The Pearson chi-square and Fisher exact tests were used to determine the differences in the distribution of the associated dental anomalies among the groups.When we compared the groups according to the various third-molar agenesis patterns, we found that agenesis of other teeth was more common in patients with agenesis of 3 and 4 third molars. Additionally, the patients with agenesis of 4 third molars exhibited maxillary lateral-incisor microdontia more frequently. Another important finding was a higher prevalence of total dental anomalies in patients with agenesis of 3 and 4 third molars compared with the control group. Permanent tooth agenesis, microdontia of maxillary lateral incisors, and total dental anomalies are more frequently associated with agenesis of 4 third molars than with the presence of third molars. Key words: Dental anomalies, tooth agenesis, panoramic radiography ÖzetBu çalışmanın amacı, bir grup Türk popülasyonunda farklı üçüncü molar agenezisi paternleri varlığındaki dental anomalileri, üçüncü molar agenezisi olmayan hastalarla karşılaştırmaktır.En az 1 adet üçüncü molar agenezisi olan 1552 hasta, üçüncü molar agenezisi paternine göre 4 gruba ayrılmış ve üçüncü molar agenezisi olmayan 402 hasta ise kontrol grubu olarak Erciyes Üniversitesi Ağız, Diş ve Çene Radyolojisi arşivinden rastgele seçilmiş-tir. Panoramik radyograflar hipodonti, hiperdonti, gömülü kalma, dilaserasyon, mikrodonti, ektopik erüpsiyon, transpozisyon ve transmigrasyon gibi dental anomalileri belirlemek için kullanılmıştır. Pearson ki-kare ve Fisher exact testleri, gruplar arasındaki dental anomalilerin dağılımındaki farklılıkları belirlemek için kullanılmıştır.Farklı üçüncü molar agenezisi paternlerine göre grupları karşılaştırdığımızda, 3 ve 4 adet üçüncü molar agenezisi olan hastalarda, diğer daimi dişlerde de daha fazla oranda

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Caries risk in patients with thalassaemia major

Abstract: The need for effective preventive measures, education and dental treatment need to be stressed for this caries risk group.

Cited by 30 publications

References 13 publications

Oral condition, chemistry of saliva, and salivary levels of Streptococcus mutans in thalassemic patients

Oral condition, chemistry of saliva, and salivary levels of Streptococcus mutans in thalassemic patients

ORAL HEALTH AND DENTOFACIAL ANOMALIES AMONG Β-Thalassemia MAJOR IN ERBIL CITY, IRAQ

Bir grup Türk popülasyonunda üçüncü molar eksikliği ile ilişkili dental anomalilerin radyografik olarak değerlendirilmesi

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