Caries prevalence in children with cleft lip and palate – a systematic review of case–control studies

Hasslöf, Pamela; Twetman, Svante

doi:10.1111/j.1365-263x.2007.00847.x

Cited by 46 publications

(31 citation statements)

References 40 publications

(37 reference statements)

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“…For deciduous teeth, data from 4 studies sug- with contradictory results. Some studies find no difference in caries prevalence between CLP and control patients, while other studies find an increased prevalence in CLP patients [Hasslöf and Twetman, 2007]. The inconsistencies found in different studies can be due to a multitude of reasons such as the multifactorial nature of dental caries, methodological differences, small sample sizes, large age ranges, patients' dental awareness, and cultural differences [Cheng et al, 2007;Hasslöf and Twetman, 2007].…”

mentioning

confidence: 87%

Caries Prevalence in Non-Syndromic Patients with Cleft Lip and/or Palate: A Meta-Analysis

2013

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Aim: To evaluate caries prevalence in non-syndromic patients with cleft lip and/or palate (CLP) in comparison with a matched non-CLP population. Methods: A literature search was conducted in order to identify articles reporting on the prevalence of caries in CLP versus non-CLP individuals. The related citations function in PubMed and reference lists of retrieved articles were used to expand the search. Only studies with a suitable matched control group were included. From each included study, study and sample characteristics were extracted, as were results. The main outcome was the score given for caries prevalence in each study, using a well-defined index. The data were entered into meta-analysis software and a meta-analysis performed using the random-effects model. Results: From the 592 articles initially identified, 7 were chosen according to preset inclusion and exclusion criteria. All of the studies were cross-sectional in nature, and used the decayed, missing, and filled (DMF/dmf) indices as the final outcomes. The included studies involved a total of 474 CLP patients aged 1.5-29 years. When looking at permanent teeth, data from 5 studies suggest that CLP patients have a higher number of DMF teeth than the controls (mean difference 1.38; p = 0.003). For deciduous teeth, data from 4 studies suggest that CLP patients have a higher number of dmf teeth than the controls (mean difference 1.51; p = 0.03). Conclusion: Non-syndromic patients with CLP tend to have higher caries prevalence, both in the permanent and the deciduous dentition, in comparison with matched non-CLP controls.

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confidence: 87%

Caries Prevalence in Non-Syndromic Patients with Cleft Lip and/or Palate: A Meta-Analysis

2013

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“…e literature on CL/P subjects and dental caries is con�icting with reports suggesting that individuals born with oral cles have a higher risk of caries [5][6][7][8][9][10][11] and there also exist studies that did not �nd any difference in caries experience between individuals born with cles and unaffected controls [12][13][14][15][16]. A recent meta-analysis on the frequency of caries in individuals born with cles was inconclusive [17].…”

Section: Introductionmentioning

confidence: 99%

Enumeration of Salivary Streptococci and Lactobacilli in Children with Differing Caries Experiences in a Rural Indian Population

Ravindran

Chaudhary²,

Gawande³

2013

ISRN Plastic Surgery

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Objectives. Compare the total salivary Streptococci and Lactobacilli counts in cle and noncle children with differing caries experiences, correlate the bacterial counts with dm/DMFT status and identify the different biotypes of Mutans Streptococci (MS). Patients. Group I included thirty subjects with dental caries (DC) and cle lip and palate (CL/P); Group II had thirty subjects with DC but without CL/P. Group III comprised a control of thirty subjects with neither DC nor CL/P. Methodology. Enumeration of total salivary Streptococci and Lactobacilli was done by the plate count method and correlation of counts with dm/ DMFT status examined. Differences in biochemical reactions were used to identify the biotypes. Results. Streptococci colonies in CL/P children with caries (64.30 ± 24.52) was signi�cantly higher than in children with no CL/P or caries (45.57 ± 16.73). No signi�cant differences in the Lactobacilli count were observed. dm/DMFT status and Streptococci counts showed a strong positive correlation whereas Lactobacilli counts showed a moderate correlation. S. mutans was the predominant biotype. Conclusions. Higher total salivary Streptococci and Lactobacilli counts exist in cle subjects with caries than in the non-cle subjects. Positive correlation between dm/DMFT scores and salivary Streptococci reinforces its role in DC. S. mutans and S. sobrinus are the biotypes more frequently associated with dental caries in children.

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“…However, when the two age groups were analyzed together the caries prevalence was 41% in children with CL/P compared to 29% in the non-cleft controls group. The results were in agreement with several previous studies (Antonarakis, Palaska et al 2013, King, Wong et al 2013, Kirchberg, Makuch et al 2014) but in contrast to others (Lucas, Gupta et al 2000, Hasslöf and Twetman 2007, Jindal et al 2011. Earlier data suggest that children with cleft lip and palate (CLP) have more caries than children with isolated cleft lip (CL) (Bian, Du et al 2001, Chapple and Nunn 2001, Besseling and Dubois 2004) but this could not be verified in the present study.…”

Section: Dental Caries Prevalence and Frequencycontrasting

confidence: 45%

“…However, conflicting results have been reported including comprehensive reviews (Paul and Brandt 1998, Lucas, Gupta et al 2000, Lages, Marcos et al 2004, Hasslöf and Twetman 2007, Jindal, McMeans et al 2011, Antonarakis, Palaska et al 2013). The present knowledge of caries prevalence in Swedish children with CL/P is sparse, and the most recent investigation dates back to the mid-80s (Dahllöf, Ussisoo-Joandi et al 1989).…”

Section: Dental Caries Prevalencementioning

confidence: 99%

Children with orofacial clefts : dental caries and health-related quality of life

Sundell¹

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Caries prevalence in children with cleft lip and palate – a systematic review of case–control studies

Abstract: This systematic review of literature was unable to find firm evidence for the assumption that CLP children have an increased prevalence of dental caries.

Cited by 46 publications

References 40 publications

Caries Prevalence in Non-Syndromic Patients with Cleft Lip and/or Palate: A Meta-Analysis

Caries Prevalence in Non-Syndromic Patients with Cleft Lip and/or Palate: A Meta-Analysis

Enumeration of Salivary Streptococci and Lactobacilli in Children with Differing Caries Experiences in a Rural Indian Population

Children with orofacial clefts : dental caries and health-related quality of life

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