Caries Incidence and Prevalence in Children Receiving Antineoplastic Therapy (Short Communication)

Pajari, Ulla; Larmas, Markku; Lanning, Marjatta

doi:10.1159/000261129

Cited by 30 publications

(24 citation statements)

References 6 publications

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“…Medication with the antracyclines and platina agents disturb dentin matrix secretion and collagen fibril formation and cause short, thin, tapered roots [22][23][24]. That chemotherapy alone can cause permanent dental retardation has been shown by many studies [12,13,16,18,[25][26][27].…”

Section: Discussionmentioning

confidence: 99%

Long-term Effects of Chemotherapy on Dental Status of Children Cancer Survivors

Németh¹,

Hermann

Kivovics

et al. 2013

Pediatric Hematology and Oncology

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Section: Discussionmentioning

confidence: 99%

Long-term Effects of Chemotherapy on Dental Status of Children Cancer Survivors

Németh¹,

Hermann

Kivovics

et al. 2013

Pediatric Hematology and Oncology

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“…Frequently these children develop stomatitis and oral mucosal ulcerations. During these periods, they may prefer sweet foods, thereby further promoting tooth decay [6]. In addition, medically compromised patients often require high carbohydrate diets in order to maintain caloric intake [35].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, medically compromised patients often require high carbohydrate diets in order to maintain caloric intake [35]. Oral hygiene may be compromised during treatment because children may be prohibited from brushing their teeth during bouts of severe thrombocytopenia and neutropenia [6,21]. Among our study population, oral hygiene may have been further compromised by the patient's age at diagnosis; nearly half of the patients were younger than 1 year when they began treatment.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, late adverse effects of therapy are becoming increasingly prevalent due to improved survival rates among infants and children; these treatment-associated sequelae include dental abnormalities. Chemotherapy [3,6,[11][12][13] and radiation therapy [1][2][3][13][14][15][16] have been implicated in various dental abnormalities, the type and severity of which reflect the timing of the insult during dental development [3,8,14]. The types and frequencies of dental sequelae in children treated at a young age for cancer have not been described extensively.…”

Section: Introductionmentioning

confidence: 99%

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Dental abnormalities in children treated for neuroblastoma

Kaste

Hopkins

Bowman

et al. 1998

Med. Pediatr. Oncol.

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“…[16][17][18][19] Most of these studies, however, had used DEFTS/DMFTS values as the only scoring method. Past caries experience is no longer the most powerful predictor for future caries incidence.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Bassir

2017

AJP

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Purpose: This study was aimed to evaluate the caries activity in children with acute lymphoblastic leukemia (ALL) undergoing maintenance stage chemotherapy courses. Materials and Methods: This is an observationalanalytical and case-control study conducted on the 27 children (4-12 years old) with ALL who were in the maintenance phase of chemotherapy in the Ahvaz Shafa Hospital, Iran. The participants of the control group, matched in terms of age, gender, and cultural status with the case group, were selected among the healthy children referred to Ahvaz Razi Hospital, Iran. The children received only a clinical dental examination without radiographs. The number of decayed (D), missing (M) and filled (F), and teeth (T) were recorded based on the WHO based DMFT index and without the use of radiography. Then, after radiographic assessment, the stimulated saliva samples were collected from the subjects to assess the salivary Streptococcus mutans counts, salivary Lactobacilli counts, and salivary buffer capacity. Results: The salivary S. mutans counts in ALL children were significantly higher than the control group (P < 0.001). In both groups, Lactobacilli counts and salivary pH and DMFT were similar (P > 0.05). Furthermore, the ALL group tended to have lower salivary flow rate than healthy subjects (P < 0.05). Conclusions: Specific oral prevention regimes should be planned with more cautions for children suffered hematology illness undergoing antineoplastic therapy with respect to children without blood problems.

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Caries Incidence and Prevalence in Children Receiving Antineoplastic Therapy (Short Communication)

Cited by 30 publications

References 6 publications

Long-term Effects of Chemotherapy on Dental Status of Children Cancer Survivors

Long-term Effects of Chemotherapy on Dental Status of Children Cancer Survivors

Dental abnormalities in children treated for neuroblastoma

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