2010
DOI: 10.1097/scs.0b013e3181f5031c
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Care Required When Using Bisphosphonates in Dental Surgical Practice

Abstract: Bisphosphonates are pharmacologic compounds characterized by high tropism to bone tissue. They affect bone metabolism by inhibition of osteoclast recruitment, proliferation, differentiation, and function. Because they can reduce bone resorption, bisphosphonates are used mainly for the treatment of osteometabolic conditions. However, the use of bisphosphonates has been associated with the onset of osteonecrosis of the jaws and indication of dental implants. As a result of this, the aim of this study was to pres… Show more

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Cited by 11 publications
(11 citation statements)
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“…25 But, osteonecrosis in patients using bisphosphonates after surgical procedures was observed. 26 Holahan et al 27 and Slagter et al 28 also agree that neither osteoporosis nor osteopenia contraindicated implant placement.…”
Section: Literature Review Osteoporosis In the Jawmentioning
confidence: 92%
“…25 But, osteonecrosis in patients using bisphosphonates after surgical procedures was observed. 26 Holahan et al 27 and Slagter et al 28 also agree that neither osteoporosis nor osteopenia contraindicated implant placement.…”
Section: Literature Review Osteoporosis In the Jawmentioning
confidence: 92%
“…The medical history was reviewed, with an emphasis on diabetes, smoking, radiation, and bisphosphonate treatment, which are common conditions with direct correlation to implant survival. [23][24][25][26] Patients completed a 14-item Oral Health Impact Profile (OHIP-14) and a Semantic Differential scale questionnaire for assessment of their oral health-related quality of life and satisfaction. The patients were asked to record their responses on a 5-point Likert scale (0 ¼ never, 1 ¼ hardly ever, 2 ¼ occasionally, 3 ¼ fairly often, 4 ¼ very often) for the OHIP-14 questionnaire.…”
Section: Medical History and Patient Satisfactionmentioning
confidence: 99%
“…Os profissionais de saúde devem ter o cuidado de saber sobre o uso e duração da utilização bisfosfonatos por seus pacientes antes de realizar a cirurgia ou colocação de implantes dentários, sendo esse um fator importante para alcançar o sucesso. (24) A definição de biomarcadores capazes de indicar o nível de risco em caso de cirurgia oral em pa-cientes que receberam bisfosfonatos também é um recurso a ser estudado melhor posteriormente. (25)…”
Section: Discussionunclassified