Cardiovascular Outcome and Mortality in Patients Undergoing Endovascular Treatment for Symptomatic Peripheral Artery Disease　― Short-Term Results of the Toma-Code Registry ―

Higashitani, Michiaki; Uemura, Yukari; Mizuno, Atsushi; Utsunomiya, Makoto; Yamaguchi, Tetsuo; Matsui, Atsushi; Ozaki, Shunsuke; Tobita, Kazuki; Tosaka, Atsushi; Oida, Akitsugu; Suzuki, Kenji; Kodama, Takahide; Jujo, Kentaro; Doijiri, Tatsuki; Takahashi, Yasuhiro; Matsuno, Seiki; Kaneko, Nobuhito; Moriguchi, Akira; Kishi, Shohei; Anzai, Hitoshi

doi:10.1253/circj.cj-18-0105

Cited by 22 publications

(15 citation statements)

References 27 publications

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“…We evaluated whether LV diastolic dysfunction is associated with risk factors of MACCE. Previous studies have reported that HF and LV systolic dysfunction were poor prognosis factors in patients with LEAD [7,8]. In the current study, MACCE, death, and hospitalization for HF occurred more frequently in patients with LV diastolic dysfunction than those without.…”

Section: Discussionsupporting

confidence: 47%

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Impact of left ventricular diastolic dysfunction on long-term outcome in patients with lower extremity artery disease

Yanaka

Akahori

Imanaka

et al. 2020

Journal of Cardiology

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The presence of lower extremity artery disease (LEAD) shows a high risk of coronary artery disease (CAD) and cerebrovascular diseases (CVD). LEAD is associated with significantly increased mortality and cardiovascular death [1][2][3][4][5]. LEAD is also a risk for heart failure (HF) [6]. Left ventricular (LV) systolic dysfunction, history of HF, and the presence of CAD were associated with an increased risk for mortality and cardiac events in patients with LEAD [7-9]. However, the impact of LV diastolic dysfunction on the long-term outcome of patients with LEAD has not been systematically studied. The aim of this study was to assess the impact of LV diastolic dysfunction on the long-term outcome in patients with LEAD. Materials and methods Study design and participantsThis study was a single center and retrospective analysis. Two hundred patients with LEAD whose ankle-brachial index (ABI) was measured within 3 months before or after echocardiography were enrolled between January 2013 and May 2015 from Hyogo College of Medicine. Exclusion criteria were ejection fraction (EF) <50 %, lack of data for echocardiography, or moderate-to-severe valvular disease. The 3-year cumulative incidence of primary and secondary endpoints was compared between LEAD patients with LV diastolic dysfunction and those without.

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Section: Discussionsupporting

confidence: 47%

“…Cardiovascular disease is a leading cause of death in patients with LEAD. A previous study reported that HF was more the cause of cardiovascular death than myocardial infarction in patients with LEAD [7]. Therefore, LV diastolic dysfunction that causes HF is considered a risk factor of cardiovascular death.…”

Section: Discussionmentioning

confidence: 97%

Impact of left ventricular diastolic dysfunction on long-term outcome in patients with lower extremity artery disease

Yanaka

Akahori

Imanaka

et al. 2020

Journal of Cardiology

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“…Clinical measurement methods in the Toma-Code registry have been previously published 8 ) . Briefly, demographic, laboratory, and procedural data were collected from each patient's hospital chart or from database by independent researchers according to predetermined definitions, and the independent study office collectively managed all data.…”

Section: Methodsmentioning

confidence: 99%

Clinical Outcome and Diverse Risk Factors for Different Therapeutic Target Locations of Peripheral Artery Disease

Higashitani

Uemura

et al. 2020

JAT

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Aim: Previous studies on peripheral artery disease (PAD) only enrolled patients with atherosclerotic lesion limited to any one of isolated locations (aortoiliac [AI], femoropopliteal [FP], and below the knee [BTK]). However, the interventions for PAD in a real-world clinical setting are often simultaneously performed for several different locations. Methods: We conducted a prospective multicenter study that included 2,230 patients with PAD who received intervention for lower extremity lesions in each area and across different areas. Patients were divided into 7 groups according to the combination of treatment locations. Overall survival (OS), major adverse limb events (MALEs), and risk factors for OS and MALEs were statistically analyzed. Results: After adjustment for confounding factors, the attributable risk for OS was similar among isolated AI, FP, and BTK treatments. MALEs increased in correlation with the number of treatment locations. Dialysis and critical limb ischemia were the common risk factors for OS and MALEs. However, the contribution of other factors such as type of drug usage was different according to treatment locations. Conclusions: In patients with PAD, OS was largely defined by comorbidities but not by lesion location. The background risk factors, underlying comorbidities, and event rates were different according to PAD location, suggesting that stratified treatment should be established for different patient populations.

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“…We used data from the Tokyo-taMA peripheral vascular intervention research COmraDE (TOMA-CODE) registry that prospectively enrolled consecutive patients with PAD who required endovascular revascularization for all indications (CLI, IC, and acute limb ischemia). Details about the TOMA-CODE registry have been described elsewhere [11]. In brief, the TOMA-CODE registry is a multicenter prospective registry that included more than 2000 consecutive patients with lower extremity PAD who underwent endovascular revascularization in Japan from August 2014 to August 2016.…”

Section: Database Explanationmentioning

confidence: 99%

Optimal cut-off value of preprocedural geriatric nutritional risk index for predicting the clinical outcomes of patients undergoing endovascular revascularization for peripheral artery disease

Yamaguchi

Ueshima

Utsunomiya

et al. 2021

Journal of Cardiology

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Cardiovascular Outcome and Mortality in Patients Undergoing Endovascular Treatment for Symptomatic Peripheral Artery Disease　― Short-Term Results of the Toma-Code Registry ―

Abstract: The preoperative clinical symptoms for EVT can predict the prognosis in patients with PAD undergoing EVT.

Cited by 22 publications

References 27 publications

Impact of left ventricular diastolic dysfunction on long-term outcome in patients with lower extremity artery disease

Impact of left ventricular diastolic dysfunction on long-term outcome in patients with lower extremity artery disease

Clinical Outcome and Diverse Risk Factors for Different Therapeutic Target Locations of Peripheral Artery Disease

Optimal cut-off value of preprocedural geriatric nutritional risk index for predicting the clinical outcomes of patients undergoing endovascular revascularization for peripheral artery disease

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Cardiovascular Outcome and Mortality in Patients Undergoing Endovascular Treatment for Symptomatic Peripheral Artery Disease ― Short-Term Results of the Toma-Code Registry ―

Abstract: The preoperative clinical symptoms for EVT can predict the prognosis in patients with PAD undergoing EVT.

Cited by 22 publications

References 27 publications

Impact of left ventricular diastolic dysfunction on long-term outcome in patients with lower extremity artery disease

Impact of left ventricular diastolic dysfunction on long-term outcome in patients with lower extremity artery disease

Clinical Outcome and Diverse Risk Factors for Different Therapeutic Target Locations of Peripheral Artery Disease

Optimal cut-off value of preprocedural geriatric nutritional risk index for predicting the clinical outcomes of patients undergoing endovascular revascularization for peripheral artery disease

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Product

Resources

About

Cardiovascular Outcome and Mortality in Patients Undergoing Endovascular Treatment for Symptomatic Peripheral Artery Disease　― Short-Term Results of the Toma-Code Registry ―