Cardiovascular Effects of Intravenous Salbutamol After Open Heart Operations

Extradural Analgesia in the Intrapartum Management of a Patient With Pulmonary Hypertension

“…Dopamine and dobutamine were available as inotropes, although high doses may impair uterine blood flow [16]. Salbutamol was available also, as there are reports of its selective action in dilating the pulmonary vasculature whilst maintaining cardiac output, albeit with tachycardia (17). We would have treated excess hypotension caused by sympathetic block with phenylephrine.…”

Comparative peripheral and coronary haemodynamic effects of rimiterol and isoprenaline.

“…Salbutamol, a f2-adrenergic receptor agonist has been shown to improve left ventricular function in patients with acute low cardiac output syndromes (Lal, Savidge, Davies Ali & Soni, 1972;Yacoub & Boyland, 1973;Wyse, Gibson & Branthwaite, 1974) and chronic congestive cardiac failure (Sharma, Goodwin & Steiner, 1977). This agent has a relatively prolonged duration of action after intravenous administration which is a disadvantage in the management of acutely ill patients with cardiac failure.…”

Similarity between the suprasystolic wideband external pulse wave and the first derivative of the intra-arterial pulse wave

“…The order was not randomized, and doses and washout periods were based on published literature to produce consistent and predictable changes in arterial pressure and arterial tone: a decrease in arterial pressure was anticipated with GTN; 27 both norepinephrine and angiotensin II were expected to increase mean pressure, but the former was expected to cause a greater increase in pulse pressure; 28 29 salbutamol was predicted to cause a decrease in diastolic pressure because of peripheral vasodilatation, and a marked tachycardia and increase in systolic pressure because of positive chronotropic and inotropic effects. 30 Pulse transit time and arterial pressure data at each time point have been published elsewhere. 21 WEP and intra-arterial recordings were made immediately before each drug and at the end of the highest dose.…”