Cardiovascular Effects of Azadirachta indica Extract

Thompson, Emmanuel B.; Anderson, C. C.

doi:10.1002/jps.2600671044

Cited by 22 publications

(9 citation statements)

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“…The people of India have known the useful properties of neem since time immemorial, and only recently have other people in more developed countries realized the value and importance of this tree to human activity [7]. For instance, various researchers have studied the medicinal properties of Azadirachta indica including its anti-pyretic effects [8,9], anti-malarial effects [10,11], anti-tumor effects [12], anti-ulcer effects [13], anti-diabetic effects [14], anti-fertility effects [15], CNS effects [16], and cardiovascular effects [17]. Preliminary investigations of leaves and bark of neem [18][19][20] cited the fact that living tissues of neem can successfully harbor endophytic fungi.…”

Section: Introductionmentioning

confidence: 99%

Endophytic Fungal Flora from Roots and Fruits of an Indian Neem Plant Azadirachta indica A. Juss., and Impact of Culture Media on their Isolation

et al. 2011

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Azadirachta indica A. Juss. (neem), native to India, is well known worldwide for its insecticidal and ethanopharmacological properties. Although endophytic microbes are known from this plant as only leaves and stems were the subjects of past reports. Now, a variety of procedures and a number of different media were used to isolate the maximum number of endophytic fungi from unripe fruits and roots. A total of 272 isolates of 29 filamentous fungal taxa were isolated at rate of 68.0% from 400 samples of three different individual trees (at locations-Az1, Az2, Az3). Mycological agar (MCA) medium yielded the highest number of isolates (95, with a 14.50% isolation rate) with the greatest species richness. Mycelia Sterilia (1, 2, 3) accounted for 11.06%, Coelomycetes 7.25%, while Hyphomycetes showed the maximum number of representative isolates (81.69%). Mycelia-Sterilia (1, 2, 3), based on their 5.8S ITS 1, ITS2 and partial 18S and 28S rDNA sequences were identified as Fusarium solani (99%), Chaetomium globosum (93%) and Chaetomium globosum (93%) respectively. Humicola, Drechslera, Colletotrichum, and Scytalidium sp. were some of the peculiar fungal endophytes recovered from this plant.

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Section: Introductionmentioning

confidence: 99%

Endophytic Fungal Flora from Roots and Fruits of an Indian Neem Plant Azadirachta indica A. Juss., and Impact of Culture Media on their Isolation

et al. 2011

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“…The medicinal properties of the plant Azadirachta indica were studied by several workers. They were Antipyretic (Khattak et al, 1985;Okpanyi and Ezeukwk, 1981), anti-malarial effect (Rochankij et al, 1985;Tella, 1977), anti tumour effect (Fujiwara et al, 1982), anti ulcer effect (Pillai and Santhakumari, 1984), anti diabetic effect (Shukla et al, 1973), antifertility effect (Sinha et al, 1984), effect on central nervous system (Singh et al, 1987) cardiovascular effect (Thompson and Anderson, 1978) and Antioxidant activity (Bandyopadhyay et al, 2002;Sultana et al, 2007). Boiled neem leaf water makes an excellent antiseptic to clean wounds, soothes, swellings and eases skin problems (Shahidi Bonjar et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.

Koona

Budida

2011

Not Sci Biol

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Azadirachta indica A. Juss (syn. Melia azadirachta) is well known in India and popularly known as Indian neem. To evaluate antibacterial potential, the agar well diffusion assay was used against Gram-negative and Gram-positive bacteria. Penicillin and Dimethyl sulfoxide were used as positive and negative controls, respectively. Methanol extract showed the highest and chloroform extract showed moderate to good antibacterial activity. Proteus vulgaris and Micrococcus luteus were the most susceptible bacteria while Bacillus subtilis was more resistant bacterium to the hexane, chloroform and methanol extracts of neem. The study recommended for the isolation and separation of bioactive compounds responsible for the antibacterial activity.

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“…The plant also has insecticidal properties (Nwude, 1986;Oliver-Bever, 1986). Moreover, the antifertility (Prakash et al, 1988;Bardhan et al, 1991;Upadhyay et al, 1993) and hypotensive with minimal negative chronotropic (Thompson and Anderson, 1978) effects of Azadirachta indica had been reported.…”

Section: Introductionmentioning

confidence: 94%

Effects of Azadirachta indica extract on gastric ulceration and acid secretion in rats

Raji

Ogunwande

Osadebe

et al. 2004

Journal of Ethnopharmacology

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Cardiovascular Effects of Azadirachta indica Extract

Cited by 22 publications

References 1 publication

Endophytic Fungal Flora from Roots and Fruits of an Indian Neem Plant Azadirachta indica A. Juss., and Impact of Culture Media on their Isolation

Endophytic Fungal Flora from Roots and Fruits of an Indian Neem Plant Azadirachta indica A. Juss., and Impact of Culture Media on their Isolation

Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.

Effects of Azadirachta indica extract on gastric ulceration and acid secretion in rats

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