Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.

Koona, Saradhajyothi; Budida, Subbarao

doi:10.15835/nsb315470

Cited by 46 publications

(29 citation statements)

References 16 publications

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“…They also observed that an inclusion of 10% of these leaves in the feed can be used as an antimicrobial substance and a natural growth-promoting agent in the diets. These results corroborate previous studies that also demonstrated the efficacy of neem leaf extracts against E. coli and S. faecalis (16) .…”

Section: Resultssupporting

confidence: 92%

USE OF NEEM (Azadirachta indica) AS A SUBSTITUTE FOR ANTIMICROBIAL DRUGS IN BROILER CHICKENS’ FEED

et al. 2019

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In the present work, we carried out an experiment aiming at evaluating the use of Neem as an antimicrobial substance in the feeds of broiler chickens. We used 240 one-day-old Cobb broiler chicks distributed in an entirely casual design, with 4 treatments, 6 repetitions and 10 birds per experimental unit, during a 21-day experimental period. Treatments consisted of a basal diet with no antimicrobial inclusion, a diet with 0.05% of tylosin, and a diet with 0.05% and 0.1% of Neem. Parameters evaluated were zootechnical performance, feed digestibility, intestinal count of Salmonella sp. and Escherichia coli, and the development of lymphoid organs. Data on the performance and metabolization of nutrients were subjected to an ANOVA and averages were compared with a post-hoc Tukey test considering α=0.05. Data on E. coli counts were analyzed with a Kruskal-Wallis test. Neem did not influence performance variables. The metabolization coefficient of dry matter and feed ethereal extract was better with tylosin (P<0.05). No growth of Salmonella was observed during the experiment. The use of Neem did not reduce E. coli population and had no influence on lymphoid organs' weight. Therefore, Neem had no effect on the performance, digestibility and intestinal microbiota of birds up to 21 days old.

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Section: Resultssupporting

confidence: 92%

USE OF NEEM (Azadirachta indica) AS A SUBSTITUTE FOR ANTIMICROBIAL DRUGS IN BROILER CHICKENS’ FEED

et al. 2019

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“…[820] This has an added advantage over the traditional root canal irrigants. [8171821] Hence, the medicinal and antimicrobial properties of the plant AI can be an alternative to NaOCl as a final root canal irrigation.…”

Section: Discussionmentioning

confidence: 99%

Influence of various herbal irrigants as a final rinse on the adherence of Enterococcus faecalis by fluorescence confocal laser scanning microscope

et al. 2013

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Aim:The aim of this study was to assess the antibacterial efficacy of three different herbal irrigants against Enterococcus faecalis.Materials and Methods:Single rooted teeth were extracted due to orthodontic and periodontal reasons. The teeth were then inoculated with E. faecalis. The teeth were randomly divided into three experimental groups and two control groups of six samples each. Group 1 specimens were treated with 5.2% sodium hypochlorite (NaOCL) for 30 min followed by 5 mmol/L Ethylenediaminetetraacetic acid (EDTA) for 5 min and saline as final irrigant. Group 2 specimens were treated with and 5.2% NaOCl for 30 min as final irrigant. Group 3 were treated with Morinda citrifolia (MC) for 30 min as final irrigant. Group 4 were treated with Azadiracta indica (AI) as final irrigant. Group 5 were treated with green tea (GT) for 30 min as final irrigant. The dentin specimens were carefully spread onto a microscope slide and stained with BacLight and examined in a confocal laser scanning microscope set to monitor fluorescein isothiocyanate and propidium iodide. A total of nine fields were examined for each treatment and the bacteria presented were counted.Statistical Analysis:Using the one-way ANOVA with multiple comparison, significantly less bacteria were found adhering to the samples treated with Neem followed by NaOCL, GT, MC, Saline.Results:AI treatment produced the maximum reduction in adherence of E. faecalis to dentin (9.30%) followed by NaOCl (12.50%), GT (27.30%), MC (44.20%) and saline (86.70%).Conclusion:Neem is effective in preventing adhesion of E. faecalis to dentin.

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“…Nimba Patra Kalka (neem leaf paste) can be used externally because of its Pitta Shamaka property and it is indicated for Vrana (wound), Krimi (worms), Kushtha (skin diseases), and Visha (poison) in Ayurvedic classics. [23] Recent researches have proved its antibacterial[24] and wound healing activity. [25] Panchavalkala Kwatha (bark decoction of five Ficus species) is indicated for cleaning the wounds,[26] so can be used externally in the condition of Bhallataka blisters.…”

Section: Discussionmentioning

confidence: 99%

Urushiol-induced contact dermatitis caused during Shodhana (purificatory measures) of Bhallataka (Semecarpus anacardium Linn.) fruit

Llanchezhian¹,

C²,

Acharya

2012

AYU

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Bhallataka (Semecarpus anacardium Linn.; Ancardiaceae) is mentioned under Upavisha group in Ayurvedic classics and it is described as a poisonous medicinal plant in Drugs and Cosmetics Act (India), 1940. Fruit of Bhallataka is used either as a single drug or as an ingredient in many compound formulations of Indian systems of medicine to cure many diseases. Tarry oil present in the pericarp of the fruit causes blisters on contact. The major constituent of the tarry oil is anacardic acid and bhilawanol, a mixture of 3-n-pentadec(en)yl catechols. Bhilawanol A and B are known as Urushiols, and also, anacardic acid is closely related to Urushiol. Urushiol-induced contact dermatitis is the medical name given to allergic rashes produced by the oil Urushiol. This paper deals with five case reports of contact dermatitis caused during different stages of Shodhana (purificatory measures) of Bhallataka fruit due to improper handling of the utensils and disposal of media used in Shodhana procedure and their Ayurvedic management. To combat these clinical conditions, the affected persons were advised external application with pounded Nimba (Azadirachta indica A. Juss.) leaves on the affected parts and internal administration of Sarivadyasava 30 ml thrice daily after food and Triphala Churna 5 g before food twice daily. Reduction of itching and burning sensation was observed after topical application.

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Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.

Cited by 46 publications

References 16 publications

USE OF NEEM (Azadirachta indica) AS A SUBSTITUTE FOR ANTIMICROBIAL DRUGS IN BROILER CHICKENS’ FEED

USE OF NEEM (Azadirachta indica) AS A SUBSTITUTE FOR ANTIMICROBIAL DRUGS IN BROILER CHICKENS’ FEED

Influence of various herbal irrigants as a final rinse on the adherence of Enterococcus faecalis by fluorescence confocal laser scanning microscope

Urushiol-induced contact dermatitis caused during Shodhana (purificatory measures) of Bhallataka (Semecarpus anacardium Linn.) fruit

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