Cardiovascular disease in autoimmune rheumatic diseases

Hollan, Ivana; Meroni, Pier Luigi; Ahearn, Joseph M.; Tervaert, Jan Willem Cohen; Curran, S.C.; Goodyear, Carl S.; Hestad, Knut; Kahaleh, Bashar; Riggio, Marcello P.; Shields, Kelly J.; Wasko, Mary Chester

doi:10.1016/j.autrev.2013.03.013

Cited by 232 publications

(186 citation statements)

References 144 publications

(22 reference statements)

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“…Symptoms of heart involvement in RD are usually subtle and underestimated, because they are attributed to the underlying systemic disease. The application of targeted treatment in RD led to a significant reduction of diseaseassociated mortality; however, the life expectancy of RD patients still remains lower, compared to general population [3] , predominantly due to high incidence of cardiovascular disease [4][5][6][7][8] .…”

Section: Cardiovascular Involvement In Rheumatic Diseases (Rd)mentioning

confidence: 99%

“How many times must a man look up before he can really see the sky?” Rheumatic cardiovascular disease in the era of multimodality imaging

Mavrogeni

Markousis‐Mavrogenis

Heutemann

et al. 2015

WJM

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Cardiovascular involvement in rheumatic diseases (RD) is the result of various pathophysiologic mechanisms including inflammation, accelerated atherosclerosis, myocardial ischemia, due to micro-or macro-vascular lesions and fibrosis. Noninvasive cardiovascular imaging, including echocardiography, nuclear techniques, cardiovascular computed tomography and cardiovascular magnetic resonance, represents the main diagnostic tool for early, non-invasive diagnosis of heart disease in RD. However, in the era of multimodality imaging and financial crisis there is an imperative need for rational use of imaging techniques in order to obtain the maximum benefit at the lowest possible cost for the health insurance system. The oligo-asymptomatic cardiovascular presentation and the high cardiovascular mortality of RD necessitate a reliable and reproducible diagnostic approach to catch early cardiovascular involvement. Echocardiography remains the routine cornerstone of cardiovascular evaluation. However, a normal echocardiogram can not always exclude cardiac involvement and/or identify heart disease acuity and pathophysiology. Therefore, cardiovascular magnetic resonance is a necessary adjunct complementary to echocardiography, especially in new onset heart failure and when there are conflicting data from clinical, electrocardiographic and echocardiographic evaluation of RD patients.

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Section: Cardiovascular Involvement In Rheumatic Diseases (Rd)mentioning

confidence: 99%

“How many times must a man look up before he can really see the sky?” Rheumatic cardiovascular disease in the era of multimodality imaging

Mavrogeni

Markousis‐Mavrogenis

Heutemann

et al. 2015

WJM

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“…Взаимосвязь ССЗ и повышения продукции СРБ про-демонстрирована в популяционных исследованиях [21], у больных РА наблюдается значительное повышение риска ССЗ [22,23]. Давно обсуждается и роль инфекции в разви-тии атеросклероза [24,25].…”

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Periodontal Diseases and Systemic Vasculitis: A View Through the Prism of Interdisciplinary Studies

Бекетова¹,

Selifanova²

2017

rsp

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“…Cardiovascular disease (CVD) in ARDs is caused by traditional and non-traditional risk factors (1). This association is the result of the complex interaction between classic risk factors, chronic inflammation and the production of autoantibodies.…”

Section: Introductionmentioning

confidence: 99%

“…Various autoimmune rheumatic diseases (ARDs), including rheumatoid arthritis, spondyloarthritis, vasculitis and systemic lupus erythematosus (SLE), are associated with premature atherosclerosis (1). Cardiovascular disease (CVD) in ARDs is caused by traditional and non-traditional risk factors (1).…”

Section: Introductionmentioning

confidence: 99%

Dyslipidemia in patients with systemic lupus erythematosus: Association with disease activity and B-type natriuretic peptide levels

Yuan

Wang

et al. 2015

Biomedical Reports

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Abstract. The aim of the present study was to evaluate the association between the levels of lipids and B-type natriuretic peptide (BNP) in systemic lupus erythematosus (SLE) patients with heart failure (HF). A total of 46 patients with active SLE and 40 healthy, age-matched control subjects were studied. BNP was measured by an immunofluorescence assay in fresh plasma. Total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, apolipoprotein (Apo) B, ApoA-I and lipoprotein(a) were assessed. Compared with the control subjects, HDL-C and ApoA-I levels were considerably decreased and TG level increased markedly from SLE patients. The average concentration of HDL-C and ApoA-I in the SLE group with HF was significantly reduced compared to those patients without HF. The results showed that the levels of HDL-C and ApoA-I in SLE patients were negatively correlated with BNP. Disease activity was associated with the TC and TG levels. The present data indicated the presence of a cardiovascular (CV) risk in active SLE with high disease activity, which was demonstrated by the high frequency of dyslipidemia and higher BNP concentrations. Therefore, dyslipoproteinemia may underlie some of the increased risk for CV disease and HF in patients with SLE.

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Cardiovascular disease in autoimmune rheumatic diseases

Cited by 232 publications

References 144 publications

“How many times must a man look up before he can really see the sky?” Rheumatic cardiovascular disease in the era of multimodality imaging

“How many times must a man look up before he can really see the sky?” Rheumatic cardiovascular disease in the era of multimodality imaging

Periodontal Diseases and Systemic Vasculitis: A View Through the Prism of Interdisciplinary Studies

Dyslipidemia in patients with systemic lupus erythematosus: Association with disease activity and B-type natriuretic peptide levels

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