Cardiopulmonary Testing and Biochemical Profile of Coronary Patients Subject to Cardiovascular Recovery Programs

The oxidative stress is linked to many chronic diseases.The aim of the study was to assess the oxidative stress in chronic suppurative otitis media. The prospective study included a group of 60 patients with different forms of chronic suppurative otitis media (CSOM), cholesteatoma recidivism and a control group of 30 healthy people. The total antioxidant capacity (TAC) and malondialdehyde (MDA) concentrations were determined in serum of thepatients. We noticed a significant lower mean of TAC levels (p[ 0.001) in patients with chronic suppurative otitis media (CSOM) with and without cholesteatoma compared to the control group. The MDA had significantly higher mean values (p[ 0.001) compared to the healthy group.The imbalance of antioxidant systems to oxidizing molecules plays an important role in the pathogenesis of CSOM with and without cholesteatoma.

Section: Resultsmentioning

confidence: 99%

The TAC and MDA Values in Patients with Chronic Suppurative Otitis Media

Şerban¹,

Bădescu²,

Palade³

et al. 2019

“…Depression is the most common form of psychic manifestation in Parkinson's disease, with a frequency of 56% in the group studied, characterized by a state of sadness, loss of hope for a long period of time, losing the interest for activities made for pleasure [22].…”

Section: Resultsmentioning

confidence: 99%

Dopaminergic Centers Neurodegeneration Biochemical and radiologic approach

Cuciureanu¹,

Popescu²,

Cuciureanu³

et al. 2019

Parkinson s disease is the second pathological neurological condition that affects millions of people annually. Up to now there is no curative treatment for this condition. Our study was conducted on a group of 99 patients who were followed periodically, clinically and radiologically for a period of three years after diagnosis with Parkinson�s disease. The results of our study show that MRI examination can be an important tool for differential diagnosis, etiopathogenicity and the prognosis of these patients. Patient follow up is required in personalizing and improving current treatment schedules of Levodopa.

“…Later, Marrian isolated from the urine a second oestrogen compound containing an extra water molecule and having the formula C 18 H 24 O 3 . It contains three hydroxyl groups, hence no ketone one [3].…”

Section: Chemistry and Terminologymentioning

confidence: 99%

The Multisystemic Effect of Oestradiol Variations

Mihălceanu¹,

Calin²,

Debita³

et al. 2019

Ovarian hormones are: oestrogenic hormone, also known as follicular hormone or female sexual hormone or chemically oestradiol; yellow body hormone, progestin or, chemically, progesterone. Oestrogenic hormone is particularly involved in the first part of the oestrus period, and the yellow body hormone in the second part (pseudo-pregnancy) and in the gestation state; the third ovarian hormone, known as relaxin, was isolated from the yellow body. Oestrogens are responsible for the development of female secondary features. Together with progesterone it controls the most important female reproductive processes. The most biologically active of oestrogens is 17b-oestradiol. Oestradiol is produced by ovarian follicles, testicles, but also by some organs such as the liver, adrenal glands, mammary glands and the brain. Oestradiol activates two specific nuclear proteins, oestrogen receptors alpha (ER�) and oestrogen receptors beta (Er�). Oestrogen receptors alpha are predominant in the mammary gland, genital apparatus, bone, nervous and cardiovascular system. Oestrogen receptors beta are found in the uterus, monocytes, tissue macrophages, colon and lung epithelial cells, epithelial cells of the prostate. The main actions of oestradiol are: endometrial proliferation, effects on the vagina and the mammary gland; it also has a role in preventing osteoporosis and reducing cardiovascular risk. Oestradiol is primarily produced in the ovary (the follicle, yellow body), but small amounts are also formed in the testicles and the cortex of the adrenals. In pregnancy, oestrogen is mainly produced by the placenta. Approximately 98% of oestradiol is linked to sex hormone binding globulin (SHBG). The level of oestradiol increases throughout the follicular phase of the menstrual cycle in close dependence with the growth and development of the ovarian follicle. For the determination of oestradiol, we conducted a study of 64 people, of which 47 women (73.43% and 17 men (26.57%). The presence of oestrogen receptors alpha indicates an increased risk of breast cancer. Breast cancer is hormone dependent, 74% of cases are oestrogen-positive receptors, and 30% of cases are progesterone-positive receptors. The main reason for the development of hyperplasia is the increase in oestrogen levels.