Cardioembolic acute myocardial infarction and stroke in a patient with persistent atrial fibrillation

Kleczyński, Paweł; Dziewierz, Artur; Rakowski, Tomasz; Rzeszutko, Łukasz; Sorysz, Danuta; Legutko, Jacek; Dudek, Dariusz

doi:10.1016/j.ijcard.2012.04.018

Cited by 19 publications

(7 citation statements)

References 8 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[3][4][5][6] Myocardial infarction (MI) is an established risk factor for AF, 7 with AF occurring in 6% to 21% of patients with MI. 8 Conversely, sporadic cases of thromboembolic acute MI also have been reported in patients with AF, [9][10][11][12][13][14][15][16] and presence of AF during acute MI has been associated with increased risk of developing in-hospital reinfarction. 8 These findings suggest that AF could also be a risk factor for MI.…”

Section: Main Outcomes and Measures-expert-adjudicated Total MI Eventmentioning

confidence: 99%

“…The rarity of coronary embolization has been attributed to differences between the caliber of the aorta and the coronary arteries, location of the coronary vessels at the root of the aorta, emergence of the coronary arteries at a right angle, the bulk and swiftness of the blood current in this portion of the aorta, and the fact that the major part of coronary filling occurs in diastole. 49 Nevertheless, several sporadic cases of MI due to coronary embolism have been reported, [9][10][11][12][13][14][15][16] suggesting that occurrence of coronary embolism could be higher than it is thought to be. Furthermore, in a postmortem study of 419 patients with MI, coronary embolization accounted for as many as 55 (13%) of these cases.…”

Section: Possible Explanationsmentioning

confidence: 99%

See 1 more Smart Citation

Atrial Fibrillation and the Risk of Myocardial Infarction

Soliman

Safford

Muntner

et al. 2015

Survey of Anesthesiology

View full text Add to dashboard Cite

IMPORTANCE-Myocardial infarction (MI) is an established risk factor for atrial fibrillation (AF). However, the extent to which AF is a risk factor for MI has not been investigated. OBJECTIVE-To Conflict of Interest Disclosures: None reported.Previous Presentation: An abstract of this article (No. 1151-49) was presented at the American College of Cardiology Annual 2013 Meeting; March 9, 2013; San Francisco, California. Additional Contributions:The authors thank the investigators, staff, and participants of the REGARDS study for their valuable contributions. A full list of participating REGARDS investigators and institutions can be found at http://www.regardsstudy.org. CONCLUSIONS AND RELEVANCE-AF is independently associated with an increased risk of incident MI, especially in women and blacks. These findings add to the growing concerns of the seriousness of AF as a public health burden: in addition to being a well-known risk factor for stroke, AF is also associated with increased risk of MI. NIH Public AccessAtrial fibrillation (AF) is a major public health problem owing to its increasing prevalence and strong association with morbidity and mortality. 1,2 Patients with AF have 4 to 5 times the risk of stroke and about double the risk of mortality compared with those without AF. [3][4][5][6] Myocardial infarction (MI) is an established risk factor for AF, 7 with AF occurring in 6% to 21% of patients with MI. 8 Conversely, sporadic cases of thromboembolic acute MI also have been reported in patients with AF, 9-16 and presence of AF during acute MI has been associated with increased risk of developing in-hospital reinfarction. 8 These findings suggest that AF could also be a risk factor for MI. However, evidence from population studies to support this assertion is lacking. Therefore, we examined the association between AF and risk of incident MI in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, 17 a large biracial population-based cohort study. MethodsThe study protocol was reviewed and approved by the participating institutions' institutional review boards. Informed consent was obtained initially on the telephone and subsequently in writing during an in-person evaluation.The goals and design of the REGARDS study have been published elsewhere. 17 Briefly, the study was designed to investigate causes of regional and racial disparities in stroke mortality, oversampling blacks and residents of the southeastern stroke belt region (North Carolina, South Carolina, Georgia, Alabama, Mississippi, Tennessee, Arkansas, and Louisiana). During the period from January 2003 to October 2007, participants (n = 30 239) were recruited from a commercially available list of residents using a combination of postal For this report, individuals with prevalent coronary heart disease (CHD) (self-reported history of MI or coronary revascularization procedure at baseline or evidence of prior MI on the baseline electrocardiogram [ECG]) were excluded. We also excluded participants with missing informatio...

show abstract

Section: Main Outcomes and Measures-expert-adjudicated Total MI Eventmentioning

confidence: 99%

Section: Possible Explanationsmentioning

confidence: 99%

Atrial Fibrillation and the Risk of Myocardial Infarction

Soliman

Safford

Muntner

et al. 2015

Survey of Anesthesiology

View full text Add to dashboard Cite

show abstract

“…В отдельных случаях у больных с ФП отмеча-лось развитие тромбоэмболического ОИМ [18]. Данная аритмия ассоциируется с признаками системного воспаления, которое может способ-ствовать протромботическому состоянию и в конечном итоге ОИМ [19].…”

Section: фибрилляция предсердий и инфаркт миокарда как сопутствующие unclassified

Aspects of antithrombotic therapy in patients with atrial fibrillation and coronary disease

Bockeria¹,

Gafurov²

2018

Ann aritmol

View full text Add to dashboard Cite

“…In some cases, patients with AF developed thromboembolic AMI [18]. This arrhythmia is associated with signs of systemic inflammation, which can contribute to the prothrombotic state and, finally, to AMI [19].…”

Section: Atrial Fibrillation and Myocardial Infarction As Concomitantmentioning

confidence: 99%

The antithrombotic therapy of atrial fibrillation in patients with coronary heart disease

Bockeria¹,

Le²

2018

Russ Open Med J

View full text Add to dashboard Cite

Coronary heart disease (CHD) is the most common cardiovascular disease, while atrial fibrillation (AF) is the most common heart rhythm disorder. These diseases have common risk factors such as hypertension, diabetes, sleep apnea, obesity and smoking. The frequency of CHD in patients with AF ranges from 17.0 to 46.5%, while the prevalence of AF among patients with CHD is low and is estimated at only 0.2-5.0%. AF is a well-known factor of unfavorable short-term and long-term prognosis in patients with acute myocardial infarction; it is associated with a significant increase in overall mortality. It is assumed that in 5-15% of cases of AF, coronary artery stenting and, accordingly, triple therapy with Aspirin, Clopidogrel or Ticagrelor and oral anticoagulant will ever be required. This requires very careful consideration of balanced antithrombotic therapy, taking into account the high risk of bleeding, the risk of stroke and stent thrombosis followed by acute coronary syndrome. Co-administration of oral anticoagulants with antiplatelet drugs, and in particular triple therapy, significantly increases the absolute risk of serious bleeding. In addition, severe bleeding is associated with a fivefold increase in the risk of adverse outcome after acute coronary syndrome. The presence of atrial fibrillation with coronary heart disease worsens the prognosis even in patients undergoing careful treatment.

show abstract

Cardioembolic acute myocardial infarction and stroke in a patient with persistent atrial fibrillation

Cited by 19 publications

References 8 publications

Atrial Fibrillation and the Risk of Myocardial Infarction

Atrial Fibrillation and the Risk of Myocardial Infarction

Aspects of antithrombotic therapy in patients with atrial fibrillation and coronary disease

The antithrombotic therapy of atrial fibrillation in patients with coronary heart disease

Contact Info

Product

Resources

About