Cardio-Protecting Effect of Natural Bioactive Compound (Polyphenol) by Inhibiting LDL Oxidation with the Scavenging of Reactive Oxygen Species (ROS)

Manna, Emili; Maiti, Smarajit

doi:10.4172/2155-9880.1000453

Cited by 2 publications

(2 citation statements)

References 18 publications

(9 reference statements)

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“…Proanthocyanidins are present primarily in the seeds, whereas resveratrol (3, 4', 5 trihydroxystilbene), a naturally occurring phytoalexin, is present mainly in grape skin at concentrations ranging from 50 to 100 mg/g (Hügel et al, 2016). Resveratrol may contribute to the heart health, other beneficial effects of grapes include, inhibition of lipid peroxidation, free radical scavenging activity, inhibition of platelet aggregation and vasorelaxation (Xia et al, 2010;Manna and Maiti, 2016) in humans.…”

Section: Grapes Grape Juice and Red Winementioning

confidence: 99%

Bioactive Functional Foods for Cardiovascular Diseases

Mustafa¹,

Ajmal²,

Naz³

et al. 2020

American Journal of Biochemistry and Biotechnology

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Cardiovascular Disease (CVD) is a chronic pathological disorder regarded as a serious health concern round the globe. It is a multifactorial disease, with a range of various causative agents, among that dietary factor is considered the most important and may to a large degree determine CVD risk. Unfortunately, it has been less widely investigated. This review outlines the general aspects of CVD, epidemiology, risk factors and emphasizes the use of functional foods for the prevention and treatment of cardiovascular diseases. It highlights the importance of various foods used in daily routine and their activity against CVDs particularly. Recent studies have investigated the consumption of various foods including soybeans, oats, psyllium, flaxseed, garlic, tea, fish, grapes, nuts, fruits, vegetables, chocolate and sterol ester enhanced margarine etc., on CVD patients and their role as a natural/socioeconomic cure over chemical based drugs. Adequate intake of these foods on a constant basis, help in decreasing the risk of cardiovascular disease by several potential mechanisms e.g., lowering blood lipid levels, improving arterial compliance, reducing low-density lipoprotein oxidation, decreasing plaque formation, scavenging free radicals and inhibiting platelet aggregation etc. This review not only emphasizes the dire need of exploring safe functional foods against alarming rise of CVD cases, but also provides future insight in the use of bioactive food components in CVD therapeutics, as they are cost effective and have fewer side effects.

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Section: Grapes Grape Juice and Red Winementioning

confidence: 99%

Bioactive Functional Foods for Cardiovascular Diseases

Mustafa¹,

Ajmal²,

Naz³

et al. 2020

American Journal of Biochemistry and Biotechnology

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“…These compounds are not considered as nutrients but much potential to prevent from chronic disease 8 . Polyphenol is predicted to restrict HMG-CoA reductase so that cholesterol synthesis in the liver is reduced so that liver cells form more receptors 11 . Flavonoid was associated with lower LDL-c susceptibility to oxidation.…”

Section: Subject Characteristicsmentioning

confidence: 99%

Consumption of 5 Servings of Fruit and Vegetable and Lipid Profile Improvement on Overweight Adolescents: a Randomized Control Trial

Jaelani¹,

Larasati²,

Yuniarti³

et al. 2019

Proceedings of the 5th International Conference on Health Sciences (ICHS 2018)

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Dyslipidemia is associated with obesity. High consumption of fruit and vegetable (FV) might promote the prevention of dyslipidemia. The aim of this study was to determine the effectiveness of 5 servings of FV to improve lipid profile on overweight adolescents. This study was an experimental study with a randomized controlled trial with a pretest-posttest control group design. The subjects were overweight adolescents with each of 17 persons for the treatment group and control group. Intervention given was the addition of 3 servings of fruit and 2 servings of vegetable (3F2V) a day for four weeks. Blood lipid profile changes were tested using ANOVA Repeated Measure test. Giving 3F2V for 4 weeks showed there was a significant decrease in total cholesterol by 15.29 mg/dl (p=0.00), LDL-c by 10.45 mg/dl (p=0.01) and there was not significantly decreased in triglycerides by 3.73 mg/dl (p=0.07). HDL-c showed reversed changes although not significantly decreased by 2.70 mg/dl (p=0.59). There was a weight loss of 0.28 kg (p=0.04).The addition of 3F2V for 4 weeks could lower total cholesterol, LDL-c,and triglycerides in overweight adolescents,but can't increase HDL-c.

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Cardio-Protecting Effect of Natural Bioactive Compound (Polyphenol) by Inhibiting LDL Oxidation with the Scavenging of Reactive Oxygen Species (ROS)

Cited by 2 publications

References 18 publications

Bioactive Functional Foods for Cardiovascular Diseases

Bioactive Functional Foods for Cardiovascular Diseases

Consumption of 5 Servings of Fruit and Vegetable and Lipid Profile Improvement on Overweight Adolescents: a Randomized Control Trial

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