2003
DOI: 10.1080/02841860310011861
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Cardiac Toxicity Associated with Capecitabine Therapy

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Cited by 11 publications
(2 citation statements)
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“…37 Fluoropyrimidines have radiosensitizing properties and, therefore, are concurrently used with external beam RT. 38 Fluoropyrimidine-associated cardiomyopathy remains a poorly understood entity. The mechanism of toxicity is possibly explained by coronary vasospasm, which is supported by in vitro evidence of vasoconstriction by FU on vascular smooth muscle cells.…”
Section: Chemotherapy Agents Associated With Ctrcdmentioning
confidence: 99%
See 1 more Smart Citation
“…37 Fluoropyrimidines have radiosensitizing properties and, therefore, are concurrently used with external beam RT. 38 Fluoropyrimidine-associated cardiomyopathy remains a poorly understood entity. The mechanism of toxicity is possibly explained by coronary vasospasm, which is supported by in vitro evidence of vasoconstriction by FU on vascular smooth muscle cells.…”
Section: Chemotherapy Agents Associated With Ctrcdmentioning
confidence: 99%
“…Cardiac symptoms usually resolve with discontinuation of FU and vasodilators. 38 The cardiotoxicity appears to be reversible after cessation of therapy. 38…”
Section: Chemotherapy Agents Associated With Ctrcdmentioning
confidence: 99%