1982
DOI: 10.1002/jps.2600710705
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Cardiac Stimulant Action of Constituents of Aloe Saponaria

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1982
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Cited by 22 publications
(16 citation statements)
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“…Cardiac stimulant activity of calcium (+)-isocitrate isolated and synthesized steroiosmers of calcium isocitrate was demonstrated and a positive inotropic effect showed in isolated guinea pig atria at a concentration of 10 -4 g/ml, only in the form of calcium salts, while no toxic effect such as arrhythmia was observed [6] . Oral administration of Aloe vera leaf extract for 21 days in alloxan induced diabetic rabbits produced a significant reduction in fasting blood glucose levels and HbA1c in the study.…”
Section: Prevention Of Heart Failure or High Blood Pressure By Aloe Vmentioning
confidence: 98%
See 1 more Smart Citation
“…Cardiac stimulant activity of calcium (+)-isocitrate isolated and synthesized steroiosmers of calcium isocitrate was demonstrated and a positive inotropic effect showed in isolated guinea pig atria at a concentration of 10 -4 g/ml, only in the form of calcium salts, while no toxic effect such as arrhythmia was observed [6] . Oral administration of Aloe vera leaf extract for 21 days in alloxan induced diabetic rabbits produced a significant reduction in fasting blood glucose levels and HbA1c in the study.…”
Section: Prevention Of Heart Failure or High Blood Pressure By Aloe Vmentioning
confidence: 98%
“…Some researchers believe that CoQ10 supplements, either by themselves or in with other drug therapies, may help prevent or treat the following conditions: 1. heart failure, 2. high blood pressure, 3. high cholesterol, 4. diabetes, 5. improve immune functions in people with AIDS, 6. improve exercise ability in people with angina, 7. help prevent migraines.…”
Section: Introductionmentioning
confidence: 99%
“…Since Aloe vera belongs to the group of crassulacean acid metabolism plant, most organic acids detected are malic, citric, succinic and tartaric acid due to C4-CO2 assimilation. In an earlier report cardiotonic constituent of Aloe saponaria, calcium isocitrate, showing positive inotropic effects on isolated cardiac muscle, was revealed [2] . On microbiology of Aloe vera, Waller TA.…”
Section: Introductionmentioning
confidence: 95%
“…A highly potent cardiotonic substance, calcium isocitrate, was isolated from Aloe saponaria, using solvent partition, nonionic porous resin, and gel permeation chromatographies. Cardiac stimulant activity of synthesized stereo-isomers of calcium isocitrate was demonstrated in isolated guinea pig atria by Yagi A., and his colleagues [11] . Dykman KD., and his colleagues reported the effect of nutritional supplements on the symptoms of fibromyalgia (FM) and chronic fatigue syndrome (CFS).…”
mentioning
confidence: 98%