“…Peritoneal insufflation with carbon dioxide (CO2) is commonly applied to establish laparoscopy, providing adequate visual and operative conditions, but also leading to increased intraabdominal pressure. Alterations in cardiovascular physiology, pulmonary function, blood gas, and acid balance resulting from pneumoperitoneal conditions have been well described [2,3,18,20,23,35]. Furthermore, macro-and microcirculatoric changes in the splanchnic area have been determined during the installation of a CO2 pneumoperitoneuni [8,[32][33][34].…”