Cardiac Muscle in Poliomyelitis

Electrocardiographic Changes in Acute Poliomyelitis in Childhood

“…Later descriptions differ little from those recorded by Saphir and Wile in 1942. Damage to myocardial fibres varies from loss of striation with aggregation of nuclei, cloudiness, and thinning to discrete areas of focal necrosis. Peale and Lucchesi (1943) observed fragmentation of muscle bundles and nuclear pyknosis. Dolgopol and Cragan (1948) described foci in which the fibres have multiple nuclei; they could not say whether the nuclei were derived from the fibres themselves or from blood vessels.…”