“…From one side, the need for restoration of systemic perfusion pushes toward higher flows but, on the other, the risk of left ventricular (LV) distension, endoventricular stasis and pulmonary oedema frightens the clinician (26,27). To the best of our knowledge, even if no studies have compared different strategies of ECMO flow regulation after cardiac arrest (hyperflow, normal flow, partial assistance), we strongly advise that the opportunity of setting the pump flow to values allowing for a rapid lactate clearance, restoration of urine output, resolution of metabolic acidosis should be carefully considered (28).…”