Cardiac death and stored electrograms in patients with third-generation implantable cardioverter-defibrillators

Grubman, Eric; Pavri, Behzad B.; Shipman, Tamara; Britton, Nancy; Kocovic, Dusan Z.

doi:10.1016/s0735-1097(98)00359-3

Cited by 46 publications

(28 citation statements)

References 15 publications

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“…A postmortem interrogation of implantable defibrillators in 83 patients with HF found that the prime mode of death was not an arrhythmia in 69% of the patients, with 16.9% dying of thromboembolic events including PE, stroke, and other forms of peripheral embolization. 49 An autopsy study in 152 patients with dilated cardiomyopathy revealed either pulmonary or systemic emboli or both in more than half of the patients. 50 …”

Section: Procoagulant State In Hfmentioning

confidence: 99%

Venous Thromboembolism in Hospitalized Patients With Heart Failure

Tsai

Khatri

et al. 2010

Circ: Heart Failure

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H eart failure (HF) is a common cardiovascular cause of hospitalizations in the United States and the most frequent reason among patients aged 65 years and older. 1 A recent report by the National Hospital Discharge Survey showed an increase in the number of hospital admissions with a diagnosis of HF from Ϸ1.3 million in 1979 to 3.9 million in 2004, with 30% to 35% of these carrying a primary diagnosis of HF. 2 Recent data from several large registries of HF hospitalizations have demonstrated in-hospital mortality as high as 4% to 7%. 3,4 Contributing to this is a significant incidence of VTE among hospitalized patients with HF. 5 In addition, VTE is associated with thromboembolic complications, which are associated with long-term sequelae including postthrombotic syndromes, venous stasis, venous ulcers, chronic thromboembolic pulmonary hypertension, and pulmonary embolism (PE). 6-8 These conditions are often associated with edema and chronic pain, which can have a significant impact on mobility and quality of life. Recurrent VTE and PE are also common complications reported in as many as 30% of patients. 9 Published information suggests that despite availability of effective therapy and existence of practice guidelines, 10,11 there is a significant underutilization of VTE prophylaxis in hospitalized patients with HF. 12-15 Analysis of the Acute Decompensated Heart Failure National Registry revealed that of 71 376 patients eligible for VTE prophylaxis only 21 847 (31%) received prophylactic regimen. 16 An analysis of the PREMIER database showed that although 79% of 34 286 patients admitted with HF received an order for VTE prophylaxis, only 15.8% received recommended appropriate prophylactic regimen in terms of the type of medications, dose, and duration of therapy. 17 These data clearly demonstrate the need for increased awareness of prevention of VTE in hospitalized patients with HF. Therefore, the purpose of this article is to review the incidence, clinical significance, and preventive treatment of VTE in hospitalized patients with HF. Rationale for VTE Prophylaxis inHospitalized Patients With HF Risk Factors for VTE in HFIn general, hospitalized patients can exhibit many of the traditional risk factors for the development of VTE including surgery, trauma, immobility, malignancy, venous compression, previous VTE, advanced age, pregnancy, medications (especially estrogen and erythropoiesis stimulating agents), obesity, myeloproliferative disorders, and acute medical illness. 18 -22 Many of these are also apparent in the hospitalized patients with HF. Characteristics of patients from the Acute Decompensated Heart Failure National Registry, which includes Ͼ160 000 patient visits, reported a median age of Ͼ75 years, active malignancy in 5%, and history of stroke or transient ischemic attack in 17%. 23 Renal insufficiency and dialysis are also associated with an increased risk for deep venous thrombosis (DVT) and PE, 24 -27 and may be present in up to one third of hospitalized patients with HF. 23 Ischemic cardi...

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Section: Procoagulant State In Hfmentioning

confidence: 99%

Venous Thromboembolism in Hospitalized Patients With Heart Failure

Tsai

Khatri

et al. 2010

Circ: Heart Failure

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“…Although many patients with ICDs eventually die from noncardiac causes, post hoc analyses have found ventricular tachycardia, ventricular fibrillation, and wide complex rhythms leading to electromechanical dissociation as a common cardiac cause of death. 24 Catheter ablation of ventricular tachycardia also remains an option in three clinical situations: (1) as adjunct to ICD, (2) as an alternative to ICD (if not a candidate), and (3) as prophylactic adjunctive therapy along with ICD. Providers may also prescribe wearable cardioverter-defibrillators, with trained nurses completing fittings of the devices in patients requiring temporary protection, or during bridging periods; survival rates seem similar to that of ICD patients.…”

Section: Arrhythmia Management and Heart Failurementioning

confidence: 99%

Team-Based Care for Managing Cardiac Comorbidities in Heart Failure

Bellam

Kelkar

Whellan

2015

Heart Failure Clinics

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“…renal disease, ca. 20-30%) [55, 56]. Table 3. refers to the European Society of Cardiology (ESC) guidelines on decision making on implantable cardioverter defibrillator (ICD) implantation for secondary prevention of SCA due to severe arrhythmia [57, 58].…”

Section: Secondary Prevention Of Scamentioning

confidence: 99%

Out-of-Hospital Cardiac Arrest –Optimal Management

Fröhlich¹,

Lyon²,

Sasson³

et al. 2014

CCR

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Out-of-hospital cardiac arrest (OHCA) has attracted increasing attention over the past years because outcomes have improved impressively lately. The changes for neurological intact outcomes has been poor but several areas have achieved improving survival rates after adjusting their cardiac arrest care. The pre-hospital management is certainly key and decides whether a cardiac arrest patient can be brought back into a spontaneous circulation. However, the whole chain of resuscitation including the in-hospital care have improved also. This review describes aetiologies of OHCA, risk and potential protective factors and recent advances in the pre-hospital and in-hospital management of these patients.

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Cardiac death and stored electrograms in patients with third-generation implantable cardioverter-defibrillators

Cited by 46 publications

References 15 publications

Venous Thromboembolism in Hospitalized Patients With Heart Failure

Venous Thromboembolism in Hospitalized Patients With Heart Failure

Team-Based Care for Managing Cardiac Comorbidities in Heart Failure

Out-of-Hospital Cardiac Arrest –Optimal Management

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