Cardiac Arrhythmias and Left Ventricular Function in Respiratory Failure from Chronic Obstructive Pulmonary Disease

Incalzi, Raffaele Antonelli; Pistelli, Riccardo; Fuso, Leonello; Cocchi, A; Bonetti, M.G.; Giordano, Alessandro

doi:10.1378/chest.97.5.1092

Cited by 42 publications

(19 citation statements)

References 23 publications

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“…Supraventricular arrhythmia has been observed to be the most frequently encountered reason of morbidity after CABG in patients with COPD when compared to the control group [13]. In our study, arrhythmia rate was observed to be significantly higher in Group 1.…”

Section: Discussionsupporting

confidence: 45%

Arterial Blood Gas Analysis in Chronic Obstructive Pulmonary Disease Patients Undergoing Coronary Artery Bypass Surgery

İlhan¹,

Günay

Özkan

et al. 2016

Turk Toraks Dergisi

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OBJECTIVES:We aimed to investigate the impact of arterial blood gas (ABG) on morbidity and mortality in chronic obstructive pulmonary disease (COPD) patients undergoing CABG surgery. MATERIAL AND METHODS:The records for 75 COPD patients who underwent elective CABG surgery our institution clinic between November 2008 to 2011 and had a forced expiratory volume in 1 second (FEV 1 ) /forced vital capacity (FVC) ≤ 70% value in the pulmonary function tests (PFT) performed prior to the surgery were evaluated retrospectively. COPD patients were divided into two groups; Group 1; FEV 1 ≥ 60% and Group 2; FEV 1 ≤ 59%. Groups were compared for mortality and adverse events after identification of other preoperative and postoperative factors that could affect mortality and adverse events. An ABG was obtained immediately before and 3 to 6 hours after surgery to study the predictive value of ABG in seperate COPD groups. RESULTS:There were no significant differences in patients with high partial pressure carbondioxide (PaCO 2 ) preoperative values compared to patients with normal values. Also there were no significant differences in patients with lower partial pressure of oxygen (PaO 2 ) preoperative values compared to patients with normal values in terms of mortality. Postoperative myocardial infarction (MI) was significantly higher in patients with low PaO 2 values (p< 0.05). CONCLUSION:In conclusion, in our study, there could not be found a relation between the degree of preoperative obstruction and mortality for COPD patients who underwent CABG surgery. ABG was not found useful for predicting mortality in COPD patients undergoing CABG surgery, but could be useful to predict postoperative MI in patients with COPD.

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Section: Discussionsupporting

confidence: 45%

Arterial Blood Gas Analysis in Chronic Obstructive Pulmonary Disease Patients Undergoing Coronary Artery Bypass Surgery

İlhan¹,

Günay

Özkan

et al. 2016

Turk Toraks Dergisi

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“…The onset of cardiac arrhythmias or stroke is a common occurrence in advanced chronic obstructive pulmonary disease (COPD) [1][2][3]. Hypoxaemia and the resulting elevated pulmonary arterial pressures are the main factors leading to cardiac involvement, and, consequently, mortality in COPD patients [4,5].…”

mentioning

confidence: 99%

Influence of exercise training on cardiac baroreflex sensitivity in patients with COPD

Costes¹,

Roche²,

Pichot³

et al. 2004

Eur Respir J

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Influence of exercise training on cardiac baroreflex sensitivity in patients with COPD. F. Costes, F. Roche, V. Pichot, J.M. Vergnon, M. Garet, J-C. Barthelemy. #ERS Journals Ltd 2004. ABSTRACT: Decreased spontaneous cardiac baroreflex sensitivity (BRS), which could lead to the onset of cardiovascular events, has been demonstrated in chronic obstructive pulmonary disease patients. This study evaluates the effects of an exercise training programme on BRS.Twenty-one chronic obstructive pulmonary disease patients (mean¡SD age 62¡9 yrs; forced expiratory volume in one second 43.6¡18.1% of the predicted value) with mild hypoxaemia (arterial oxygen tension 8.96¡1.18 kPa) were compared to 18 healthy agematched subjects. BRS was calculated as the slope of the baroreflex sequences between spontaneous changes in systolic blood pressure and subsequent consecutive relative risk deviation length, and was measured in the supine position and following head-up tilt for sympathetic stimulation.Pulmonary function test results and blood gas levels, measured only in patients, did not change after the training programme. Exercise training increased the maximal sustained workload (16.5%) and peak oxygen consumption (20.5%). Before training, BRS was lower in patients than in controls (2.7¡1.5 versus 7.8¡4.9 ms?mmHg -1 ) and tilting induced a smaller reduction in BRS (13 versus 34%). After training, BRS increased to 3.4 ¡ 2.6 ms?mmHg -1 in patients but remained lower than in controls. The response to the tilt test remained unchanged after training.It is concluded that, in chronic obstructive pulmonary disease patients, exercise training is associated with a gain in spontaneous baroreflex sensitivity, reflecting cardiovascular benefits.

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“…KOAH'lı hastalarda ise yüksek AF prevelansını işaret eden raporlar mevcuttur. KOAH'ın postoperatif AF gelişimine etkisinin ise bu hasta grubunda premature atriyal kontraksiyon insidansının yüksek olmasına, kan oksijen ve karbondioksit basınçlarında meydana gelen akut değişimlere bağlı olabileceği bildirilmiştir (5,22) . Bizde de postoperatif AF görülen grup ile gö-rülmeyen grup karşılaştırıldığında DM, HT, KOAH gibi predispozan faktörler açısından benzer olarak izlendi.…”

Section: Discussionunclassified

Evaluation of Risk Factors for Atrial Fibrillation Occurring After Coronary Bypass Surgery

Yanartaş¹

2015

Kosuyolu Heart Journal

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Giriş: Postoperatif atriyal fi brilasyon (AF) kardiyak operasyonlar sonrasında mortalite ve morbiditeye etki eden önemli bir faktördür. Bu çalışmada, kliniğimizde yapılan koroner baypas operasyonları sonrası AF geliş-me sıklığının ve risk faktörlerinin araştırılması amaçlanmıştır. Hastalar ve Yöntem:Kliniğimizde Ocak 2011-Nisan 2011 yılları arasında yapılan koroner baypas operasyonlarının kayıtları retrospektif olarak incelenmiştir. Çalışmaya 211 hasta dahil edilmiştir. Postoperatif AF gelişen hastalar Grup I, gelişmeyen hastalar ise Grup II olarak sınıfl andırılmıştır. İki grup, diabetes mellitus (DM), hipertansiyon (HT), sigara kullanımı, kronik obstrüktif akciğer hastalığı (KOAH), distal anastomoz sayısı ve aort kros klemp süresi (AKK) açısından karşılaştırılmıştır.Bulgular: Grup I'deki hastaların 33 (%68)'ü erkek, 15 (%32)'i kadın hasta, Grup II'deki hastaların 119 (%73)'u erkek, 44 (%27)'ü kadındı. Ortalama yaş Grup I'de 66.2 ± 10.8 yıl, Grup II'de 60.4 ± 9.3 yıl olarak saptandı (p< 0.05). Gruplar arasında DM, sigara alışkanlığı, HT ve KOAH açısından anlamlı fark yoktu. Distal anastomoz sayısı Grup I'de ortalama 5.6 ± 2.1, Grup II'de ise ortalama 3.5 ± 2.4 idi (p< 0.05). AKK süresi I. Grupta ortalama 58.2 ± 29.1 dakika, II. Grupta ortalama 39.6 ± 18.4 dakika olarak bulundu (p< 0.05). Ortalama yatış süresi Grup I'de 5.2 ± 2.6 gün, Grup II'de 4.5 ± 3.1 gün olarak belirlendi. Erken dönem mortalite izlenmedi (Taburculuk sonrası ilk bir ay). Yaş, AKK ve distal anastomoz sayısı, postoperatif AF gelişimini etkileyen temel faktörler olarak belirlendi. Evaluation of Risk Factors for Atrial Fibrillation Occurring After Coronary Bypass SurgeryABSTRACT Introduction: Postoperative atrial fi brillation (AF) is an important determinant of mortality and morbidity after cardiac surgery. In this study, our aim was to examine the incidence of and risk factors for AF developing after coronary bypass surgery. Patients and Methods:Patients undergoing coronary bypass surgery between January 2011 and April 2011 in our department were examined retrospectively. A total of 211 patients were included in the study. Patients with postoperative AF comprised Group I, while those without comprised Group II. The two groups were compared in terms of a number of potential risk factors for AF including the presence of diabetes mellitus (DM), hypertension (HT), cigarette smoking, chronic obstructive pulmonary disease (COPD), number of distal anastomoses, and aortic cross clamp time (ACC).Results: There were 33 (68%) were male and 15 (32%) female patients in Group I and 119 (73%) male and 44 (27%) female patients in Group II, respectively. Mean age was 66.2 ± 10.8 years in Group I and 60.4 ± 9.3 years in Group II (p= 0.001). There were no signifi cant differences between study groups in terms of the incidence of DM, smoking, HT or COPD. Number of distal anastomoses were 5.6 ± 2.1 in Group I and 3.5 ± 2.4 in Group II (p< 0.05). ACC time was 48.2 ± 29.1 and 59.6 ± 18.4 minutes in Groups I and II, respectively (p< 0.05). Mean duration of hospitali...

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Cardiac Arrhythmias and Left Ventricular Function in Respiratory Failure from Chronic Obstructive Pulmonary Disease

Cited by 42 publications

References 23 publications

Arterial Blood Gas Analysis in Chronic Obstructive Pulmonary Disease Patients Undergoing Coronary Artery Bypass Surgery

Arterial Blood Gas Analysis in Chronic Obstructive Pulmonary Disease Patients Undergoing Coronary Artery Bypass Surgery

Influence of exercise training on cardiac baroreflex sensitivity in patients with COPD

Evaluation of Risk Factors for Atrial Fibrillation Occurring After Coronary Bypass Surgery

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