Cardiac and Respiratory Motion-induced Artifact in Myocardial Perfusion SPECT

Okuda, Koichi; Nakajima, Kénichi; Kikuchi, Akihiro; Onoguchi, Masahisa; Hashimoto, Mitsumasa

doi:10.17996/anc.17-00005

Cited by 9 publications

(3 citation statements)

References 15 publications

(9 reference statements)

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“…In other studies, a segmentation was applied by the threshold for different spheres with volumes from 10 mm to 37 mm of diameter, and the reported threshold values between 40% and 45% depending on the S/B ratio, volume and sphere diameter; similar parameters were used in this work. Considering these parameters is possible to apply this methodology in clinical studies, especially in treatments that imply respiratory motion [2], [17], perfusion in cardiology studies [3], radioembolization in liver with microspheres of 90Y [18], [19]. A threshold procedure is necessary for a correct image delineation in segmentation, including the area and volume delimitation to improve the resolution for SPECT/CT studies.…”

Section: Volume's Evaluation In Spect and Ctmentioning

confidence: 99%

Effects of movement artifacts in nuclear hybrid modalities for image diagnostic

Sánchez

Escudero

Morán

et al. 2022

J. Phys.: Conf. Ser.

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In the obtention of medical images, the patients’ movement can modify the identification of the body components in an image. The combination of imaging techniques may not always be a solution to improve the imaging quality; therefore, an artifact analysis is commonly required prior to applying an imaging procedure in patients. In this work, we systematically evaluated the movements’ artifacts caused by the patients’ breathing during the images acquisition and their impact on the fusion of SPECT and CT modalities. We used a specific phantom placed on a platform to emulate the respiratory movement, finding artifacts not appreciable under the standard condition used to obtain the SPECT images due to its low spatial resolution. The artifacts produced a deformation of elements on the images. Therefore, image processing was necessary to identify the registration accuracy with SPECT and CT modalities in two states (phantom at rest and for a phantom with simulated respiratory movements). A systematic difference was obtained for the first case (11.7 mm), and a range of (7.4 mm to 16.1 mm) for the second one. For the volumes’ evaluation, the optimal threshold value for CT was 0.40 and for SPECT was 0.25, giving a rapid solution to reduce the artifacts’ impact on medical images.

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Section: Volume's Evaluation In Spect and Ctmentioning

confidence: 99%

Effects of movement artifacts in nuclear hybrid modalities for image diagnostic

Sánchez

Escudero

Morán

et al. 2022

J. Phys.: Conf. Ser.

View full text Add to dashboard Cite

show abstract

“…The respiratory motion has been demonstrated as a major cause of the motion blurring for cardiac SPECT as the long acquisition time of SPECT would cover multiple respiratory cycles . The reported range of respiratory motion could be 9–27.2 mm in the cranial‐caudal direction .…”

Section: Introductionmentioning

confidence: 99%

Interpolated CT for attenuation correction on respiratory gating cardiac SPECT/CT — A simulation study

2019

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Purpose Respiratory gated four‐dimensional (4D) single photon emission computed tomography (SPECT) with phase‐matched CT reduces respiratory blurring and attenuation correction (AC) artifacts in cardiac SPECT. This study aims to develop and investigate the effectiveness of an interpolated CT (ICT) method for improved cardiac SPECT AC using simulations. Methods We used the 4D XCAT phantom to simulate a population of ten patients varied in gender, anatomy, 99mTc‐sestamibi distribution, respiratory patterns, and disease states. Simulated 120 SPECT projection data were rebinned into six equal count gates. Activity and attenuation maps in each gate were averaged as gated SPECT and CT (GCT). Three helical CTs were simulated at end‐inspiration (HCT‐IN), end‐expiration (HCT‐EX), and mid‐respiration (HCT‐MID). The ICTs were obtained from HCT‐EX and HCT‐IN using the motion vector field generated between them from affine plus b‐spline registration. Projections were reconstructed by OS‐EM method, using GCT, ICT, and three HCTs for AC. Reconstructed images of each gate were registered to end‐expiration and averaged to generate the polar plots. Relative difference for each segment and relative defect size were computed using images of GCT AC as reference. Results The average of maximum relative difference through ten phantoms was 7.93 ± 4.71%, 2.50 ± 0.98%, 3.58 ± 0.74%, and 2.14 ± 0.56% for noisy HCT‐IN, HCT‐MID, HCT‐EX, and ICT AC data, respectively. The ICT showed closest defect size to GCT while the differences from HCTs can be over 40%. Conclusion We conclude that the performance of ICT is similar to GCT. It improves the image quality and quantitative accuracy for respiratory‐gated cardiac SPECT as compared to conventional HCT, while it can potentially further reduce the radiation dose of GCT.

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“…We acquired virtual myocardial perfusion SPECT images using the 4D XCAT digital phantom through simulating medical imaging nuclear detectors (SIMIND) Monte Carlo software 5 to authenticate a novel program that can evaluate ECG-gated myocardial perfusion SPECT data. 6 Figure 1 shows an example of normal myocardial perfusion images derived from a clinical patient and a digital phantom. The image quality of the digital phantom was essentially equivalent to that of the clinical patient.…”

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confidence: 99%