“…It is, however, clear from the response of certain of our patients (Pochin, 1950) and of cases previously described (Howes and Foote, 1949;Horn and Ravdin, 1951;Sorrentino et al, 1951) that the treatment can be valuable, and probably curative in some patients (Seidlin et al, 1951) even when metastasis has occurred before radio-iodine is given. It is also clear that it can be effective in a significant proportion of all thyroid carcinomata, and not only in occasional cases.…”