Indications for Radio-iodine Treatment of Thyroid Carcinoma

Natural History of Thyroid Carcinoma

“…In our series 1311 therapy was used in 30 of the 86 patients with a differentiated lesion. As expected, it was used most often in those lesions with abundant colloid, although Pochin et al (1952) have shown that there is not always correlation between radioiodine uptake and the presence of colloid-filled follicles. Autoradiography can give more precise evidence of the suitability of a malignant lesion for radioiodine treatment when a metastasis can be partly or wholly removed for examination after a generous tracer dose of 13 II.…”

“…Radioiodine has now been used in the treatment of differentiated thyroid cancer for well over ten years (Dobyns and Maloof, 1951 ;Maloof et al, 1956 ;Pochin, 1957;Taylor and Goolden, 1959). The principle of reserving such treatment for selected patients with metastatic disease is a sound one, while the primary tumour with its immediate extensions is best treated by conventional surgical methods.…”

A scanning apparatus for the localization of gamma emitting isotopes in vivo

“…This type of measurement is a simple and reproducible method of studying the distribution of radioiodine in patients with functioning thyroid carcinoma metastases (28). For this purpose, the detector head is provided with a slot-formed collimator and moves over the body in only one direction with a speed of 8.75 or 17.5 cm per minute.…”

Ein empfindliches Verfahren zum Nachweis von Schilddrüsenmalignommetastasen mit J131

“…Darauf weisen die von P o c h i n und Mitarb. (7) angegebenen Zahlen hin, die zwischen 25 und 30°/o liegen.…”