Carcinoma of the cervix uteri, a clinical and pathologic study

The Treatment of Carcinoma of the Cervix in Detroit, Michigan

“…Hetlly (10) reports that at least twothirds are clinically unfavorable when first seen. Fluhmann (7) says that in any series of cases, those in which 60 per cent five-year cures may be expected amount to only 1 to 5 per cent of the total.…”

History of Gynecologic Pathology XXVIII

“…Fluhmann hit the ground running at Stanford; he published his first paper (12) and was promoted from Instructor to Assistant Professor in the fall of 1926. In 1927, Fluhmann published 3 more papers, 2 of these related to cervical pathology (13,14), perhaps a premonition of the arena for which he would later make most of his important pathologic contributions. He was immediately promoted again ( considerable effort into saving the faltering Stanford residency training program and achieving full accreditation (2,10).…”

“…In fact, after a small flurry of gynecologic pathology publications at the beginning of his career (13)(14)(15)(16)(17)(18)(19)(20), his contributions throughout the 1930s and 1940s mostly focused on the etiology of uterine bleeding, reproductive endocrinology, the role of anterior pituitary hormones, and studies in rats. His primary contribution to pathology and laboratory medicine during the 1930s and 1940s, was possibly his shortlived ''Fluhmann test,'' a bioassay for measuring urine estrogen levels last cited in 1943 (21).…”

“…An early paper is of note in part because the criteria he proposed for the rare primary squamous cell carcinoma of the endometrium have been widely used over the years sometimes being referred to as ''Fluhmann's postulates'' (16). His interest in epithelial lesions of the uterine cervix spanned essentially his entire career beginning with a 1927 paper on 110 cases of carcinoma of the cervix (13). The varied gross and histologic features of these tumors are described although consideration of the latter is hindered by outdated terminology.…”