Carcinoma in situ of the male breast.

Abstract

SUMMARY Two cases of carcinoma in situ of the male breast are described: in one patient it arose as a complication of gynecomastia; in the other, it occurred 'de novo' and proceeded to infiltration with widespread metastases. We reviewed 233 cases diagnosed clinically and histopathologically as gynecomastia to see if we could discover other instances of malignant transformation but none was found. Thirty-two cases of infiltrating male breast cancer were also examined. In 11 there was associated intraduct change. In only one of the 32 cases was there evidence of associated microscopic gynecomastia.

Ductal carcinoma in situ in a 16-year-old adolescent boy with gynecomastia: a case report

“…In this case, a focus of DCIS and bilateral atypical ductal hyperplasia were also found. The association of DCIS and gynecomastia has been reported in the literature only twice, both in adult men, a 32-year-old and a 60-year-old [9,10].…”

Ductal carcinoma in situ (DCIS) in the male breast

“…15 Particularly with regard to the issue of the frequency of high grade DCIS of comedo or noncomedo type, substantial differences exist in the literature. 15,17,32 The objective of the current study was to evaluate the morphologic spectrum of DCIS in the male breast. Because the male breast characteristically lacks lobules (terminal duct lobular units [TDLU]) in which a majority of DCIS cases originate in the female breast, 33 the potentially significant impact of this structural difference on the localization and morphology of DCIS in the male breast is discussed.…”

Ductal carcinoma in situ in a 15-year-old boy with gynaecomastia: a case report

“…This lesion is extremely rare in men, especially in association with gynaecomastia [4,5], and in fact, literature reports only two cases in adults and one during adolescence [6][7][8].…”