Carcinoid tumour of the ampulla of Vater presenting as acute pancreatitis.

Dixon, J M; Chapman, Roger W.; Berry, A. R.

doi:10.1136/gut.28.10.1296

Cited by 16 publications

(2 citation statements)

References 7 publications

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“…1 Fewer than 120 cases of ampullary neuroendocrine tumors have been reported in the literature, mostly as isolated case reports. [2][3][4][5][6] Because they are so rare, significant questions regarding their natural history remain unanswered. For example, the prognostic significance of tumor size, depth of invasion, and regional lymph node metastases is largely unknown.…”

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confidence: 99%

Neuroendocrine Tumors of the Ampulla of Vater

Carter¹

2009

Arch Surg

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This is one of the largest series of neuroendocrine tumors of the ampulla. Preoperative biopsy was accurate, but computed tomographic scans were insensitive in detecting nodal metastases. Unlike duodenal carcinoid tumors, hypersecretion syndromes were absent and small tumor size did not preclude locoregional metastases. Tumor grade predicted survival. We recommend pancreaticoduodenectomy for this disease, with local resection reserved for mobile, superficial lesions.

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Neuroendocrine Tumors of the Ampulla of Vater

Carter¹

2009

Arch Surg

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“…The etiology of AP is complex and about 10% of patients are idiopathic with the exclusion of all the common causes (2). Followup of these cases may lead to tumors and it was reported that AP might be an early manifestation of many types of tumors, including pancreatic cancer, ampullary carcinoma, intraductal papillary mucinous neoplasms (IPMN), non-Hodgkin lymphoma (NHL), metastatic lung cancer, and parathyroid carcinoma (3)(4)(5)(6)(7)(8). Disappointingly, most were case reports, and there was a lack of data regarding typical presentations and diagnostic clues (such as elderly, mild AP) in the early stage of those tumors.…”

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Clinical characteristics and outcome of tumor-associated acute pancreatitis: a single-center cohort study

Xiong¹,

Zhao²,

Han³

et al. 2021

Ann Transl Med

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Background: What features should alert clinicians to suspect underlying tumors in patients with acute pancreatitis (AP) was largely unknown. This study aimed to assess the clinical characteristics and outcome in patients with tumor-associated AP.Methods: Patients who presented with AP and were diagnosed with tumor after admission were included according to the inclusion and exclusion criteria and followed up by hospital notes, telephone, WeChat and/ or e-mail. The clinical characteristics and outcome were analyzed with multivariable logistic regression and were compared with AP patients without tumor.Results: Out of a cohort of 1,792 AP patients we identified 103 who had a neoplastic etiology. The 103 patients had a median age of 57 (range, 13-81) and 65 were males. AP was mild in 92 patients, moderately severe in 7 and severe in 4. The three most common tumors included pancreatic cancer (PC) (40), periampullary carcinoma (PAC) (25), and neoplastic pancreatic cysts (NPC) (22). The following ranked features were predictive of a tumor etiology: dilation of main pancreatic duct (MPD) (

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