Carboxylic acid functional group analysis using constant neutral loss scanning-mass spectrometry

Development of a liquid chromatographic method based on ultraviolet–visible and electrospray ionization mass spectrometric detection for the identification of nitrocatechols and related tracers in biomass burning atmospheric organic aerosol

“…The two first‐eluting compounds (Figs. (A) and (B)) both reveal the loss of 44 units, corresponding to the loss of CO 2 ( m/z 138) consistent with the presence of a carboxylic group . Subsequent fragmentation of m/z 138 leads to the loss of NO resulting in an ion at m/z 108 (not shown), and a pattern similar to that observed for the deprotonated form of 4NP (Fig.…”

“…(A)). These (−)ESI‐MS n (n = 2 and 3) data allowed us to conclude that these two compounds contain a carboxyl, a hydroxy and an aromatic nitro group . This led us to consider nitrosalicylic acid isomers, i.e.…”

A General and Efficient Heterogeneous Gold‐Catalyzed Hydration of Nitriles in Neat Water under Mild Atmospheric Conditions

“…As we showed in a previous work devoted to carboxylic acid quantification,28 the constant neutral loss scanning tandem mass spectrometry (CNLS–MS/MS) technique revealed to be an interesting alternative to overcome these difficulties. The neutral loss scanning mode consists in monitoring the loss of a neutral fragment produced by the fragmentation of a precursor ion in a collision cell.…”

In-cloud processes of methacrolein under simulated conditions – Part 2: Formation of secondary organic aerosol

“…The collisioninduced dissociation of m/z 187 − mainly leads to two predominant daughter ions at m/z 143 − and 87 − (Table 1). The m/z 143 − daughter ion, resulting from the loss of CO 2 as a neutral fragment (44 uma), indicates the presence of at least one carboxylic acid functional group (Dron et al, 2007). The m/z 87 − daughter ion suggests that at least one of the two products associated with m/z 187 − include in its chemical structure the pyruvate as a structural subunit.…”