Carbonate interlayered hydrotalcites-enhanced peroxynitrous acid chemiluminescence for high selectivity sensing of ascorbic acid

Abstract

In this study, Mg-Al-carbonate layered double hydroxides (denoted as Mg-Al-CO(3) LDHs) were found to catalyze the chemiluminescence (CL) emission from peroxynitrous acid (ONOOH). The enhanced CL signals resulted from the concentration of peroxynitrite (ONOO(-)) onto the LDHs surface by electrostatic attraction, meaning that ONOO(-) can interact with the intercalated carbonate easily and effectively. Moreover, ascorbic acid can react with ONOO(-), or its decomposition products (e.g., ˙OH and ˙NO(2)), resulting in a decrease in the CL intensity from the Mg-Al-CO(3) LDHs-catalyzed ONOOH reaction. Based on these findings, a sensitive, selective and rapid CL method was developed for the determination of ascorbic acid using Mg-Al-CO(3) LDHs-catalyzed ONOOH as a novel CL system. The CL intensity was proportional to the concentration of ascorbic acid in the range from 5.0 to 5000 nM. The detection limit (S/N = 3) was 0.5 nM and the relative standard deviation (RSD) for nine repeated measurements of 0.1 μM ascorbic acid was 2.6%. This method has been successfully applied to determine ascorbic acid in commercial liquid fruit juices with recoveries of 97-107%. This work is not only of importance for a better understanding of the unique properties of LDHs-catalyzed CL but also of great potential for extensive applications in many fields, such as luminescence devices, bioanalysis, and labeling probes.

An “on-off-on” fluorescent nanoprobe for recognition of chromium(VI) and ascorbic acid based on phosphorus/nitrogen dual-doped carbon quantum dot

“…To this end, the determination of AA content in pharmaceutical preparations and food products has received considerable attention, and a straightforward and effective method for AA detection in daily analysis is urgent to be developed. To date, numerous methods for AA detection have been developed, including titration with an oxidizing agent [10], electrochemistry [11], spectrophotometry [12], chromatography [13], chemiluminescence [5,14], enzymology [15] and capillary electrophoresis [16]. Nevertheless, more simple, effective and sensitive methods for AA detection in food samples are still in urgent demand.…”

“…Furthermore, the PNCQDs/Cr(VI) mixture could act as a "turn-on" fluorescence nanoprobe (off-on, Scheme 1) for the determination of AA. Comparing to other AA probe [5,[12][13][14]16], it possess high sensitivity (LOD = 1.35 µmol/L), low cost, high selectivity and fast response (within 1 min).…”

Metal–Organic Framework‐Derived Copper Nanoparticle@Carbon Nanocomposites as Peroxidase Mimics for Colorimetric Sensing of Ascorbic Acid

“…[16] To date, various methods have been developed for the detection of ascorbic acid, including electrochemical, [17] chromatographic, [18] fluorometric, [19] and chemiluminescence methods. [20] These methods are sensitive and highly specific, but the requirement of expensive and sophisticated instruments limits their further applications. Colorimetric detection would be a more desirable method due to its low cost, simplicity, and practicality.…”

Chemiluminometric determination of ascorbic acid in pharmaceutical formulations exploiting photo‐activation of GSH‐capped CdTe quantum dots

“…Because of the relevance of antioxidants, for example, ascorbic acid (AA), several flow‐based methods have been proposed for antioxidant determination in different matrices, some of them exploiting the advantageous features of the flow analysis/CL combination. In this context, flow‐based analytical procedures relying on the reactions of luminol , lucigenin , Rhodamine B , permanganate and peroxynitrous acid are highlighted.…”